Laser in situ keratomileusis flap complications using mechanical microkeratome versus femtosecond laser: Retrospective comparison
Laser in situ keratomileusis flap complications using mechanical microkeratome versus femtosecond laser: Retrospective comparison
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DOI：
10.1016/j.jcrs.2010.05.027
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发表时间：
2010-11-01
影响因子：
2.8
通讯作者：
Chang, Joann C.
中科院分区：
文献类型：
--
作者：
Moshirfar, Majid;Gardiner, Jeffrey P.;Chang, Joann C.
目的比较使用零压缩微角膜刀和飞秒激光制作激光原位角膜磨成形术（LASIK）皮瓣术后并发症的发生率。USADESIGN循证manuscriptMETHODS皮瓣并发症率是评估在最初18个月的经验使用零压缩一步(Hansatome)或飞秒激光(IntraLase FS60)皮瓣creationRESULTS皮瓣并发症率为14 2%一步组和飞秒激光15 2%组(P = 5437)术中皮瓣并发症率为5 3%和2 9%,(P = 0111),分别与术后皮瓣并发症率,两组术后最常见的并发症是弥漫性板层性角膜炎（DLK）（6 %，微角刀组，10 %，飞秒激光组）（P = 0002）。结论两组患者的总并发症发生率相近，但两组患者的术后并发症发生率差异无统计学意义（P = 0201）。微角化组术中上皮缺损明显增多，飞秒激光组术后DLK明显增多
PURPOSE To compare the incidence of flap complications after creation of laser in situ keratomileusis (LASIK) flaps using a zero-compression microkeratome or a femtosecond laserSETTING John A Moran Eye Center, Department of Ophthalmology, University of Utah, Salt Lake City, Utah, USADESIGN Evidence-based manuscriptMETHODS The flap complication rate was evaluated during the initial 18 months of experience using a zero-compression microkeratome (Hansatome) or a femtosecond laser (IntraLase FS60) for flap creationRESULTS The flap complication rate was 14 2% in the microkeratome group and 15 2% in the femtosecond laser group (P = 5437) The intraoperative flap complication rate was 5 3% and 2 9%, respectively (P = 0111), and the postoperative flap complication rate, 89% and 12 3%, respectively (P = 0201) The most common intraoperative complication in the microkeratome group was major epithelial defect/sloughing, the rate (2 6%) was statistically significantly higher than in the femtosecond laser group (P = 0006) The most common postoperative complication in both groups was diffuse lamellar keratitis (DLK) (6 0%, microkeratome, 10 6%, femtosecond laser) (P = 0002)CONCLUSION Although the total complication rates between the 2 groups were similar, the microkeratome group had significantly more epithelial defects intraoperatively and the femtosecond laser group had significantly more DLK cases postoperatively