Microbial resolution and asymmetric reduction related to optically active 1,3-diphenylpropane-1,3-diol

Microbial resolution and asymmetric reduction related to optically active 1,3-diphenylpropane-1,3-diol
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与光学活性 1,3-二苯基丙烷-1,3-二醇相关的微生物分辨率和不对称还原

DOI:
10.1039/c39870000334
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发表时间:
1987
期刊:
Journal of The Chemical Society, Chemical Communications
影响因子:
--
通讯作者:
H. Chikamatsu
H. Chikamatsu
中科院分区:
--
文献类型:
--
作者:
Koji Yamamoto;Hiroyuki Ando;H. Chikamatsu

文献摘要

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An efficient microbial resolution of 1,3-diphenylpropane-1,3-diol (4) has been achieved by exposing the corresponding diacetate to Trichoderma viride; a reductive cleavage of chiral acetals (6) derived from (4) with hydride reagent (Br2AlH, Cl2AlH) affords optically active alcohols (8) of high enantiomeric purities.