3 CASES OF NEONATAL MENINGITIS CAUSED BY ENTEROBACTER-SAKAZAKII IN POWDERED MILK

3 CASES OF NEONATAL MENINGITIS CAUSED BY ENTEROBACTER-SAKAZAKII IN POWDERED MILK
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DOI:
10.1128/jcm.27.9.2054-2056.1989
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发表时间:
1989-09-01
影响因子:
9.4
通讯作者:
STEINGRIMSSON, O
STEINGRIMSSON, O
中科院分区:
医学2区
文献类型:
--
作者:
BIERING, G;KARLSSON, S;STEINGRIMSSON, O

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冰岛雷克雅未克国立大学医院新生儿重症监护室报告了三例坂崎肠杆菌引起的新生儿感染病例。这些感染发生在1986年和1987年的9个月期间。其中两名出生时正常的新生儿幸存下来,但留下了脑损伤。第三个患有唐氏综合症和严重的心脏畸形,死亡。同样的微生物也从健康新生儿的腹股沟和肛门拭子中生长出来。E.坂崎没有从新生儿病房或牛奶厨房的任何环境来源中分离出来,但它是从医院使用的几批奶粉配方中生长出来的。四个E。从新生儿中分离的坂崎菌株与从配方中生长的22个菌株无法区分。它们的生物型、质粒DNA图谱和电泳图谱完全相同。
Three cases of neonatal infection caused by Enterobacter sakazakii are reported from the Department of Neonatal Intensive Care, the National University Hospital, Reykjavik, Iceland. These infections occurred during a 9-month period in 1986 and 1987. Two of the neonates, who were normal at birth survived but were left with brain damage. The third, who had Down''s syndrome and severe cardiac malformations, died. The same organism was also grown from groin and anal swabs from a healthy neonate. E. sakazakii was not isolated from any environmental sources in the neonatal wards or in the milk kitchen, but it was grown from several lots of powdered-milk formula used in the hospital. The four E. sakazakii strains isolated from the neonates were indistinguishable from 22 strains grown from the formula. Their biotypes, plasmid DNA profiles, and antibiograms were identical.