Reprogramming Interferon Regulatory Factor Signaling in Cardiometabolic Diseases
Reprogramming Interferon Regulatory Factor Signaling in Cardiometabolic Diseases
复制标题
心脏代谢疾病中干扰素调节因子信号的重编程
DOI：
10.1152/physiol.00038.2016
复制
发表时间：
2017
期刊：
影响因子：
8.4
通讯作者：
Li Hongliang
中科院分区：
文献类型：
--
作者：
Zhang Yaxing;Li Hongliang
Interferon regulatory factors (IRFs) are evolutionarily conserved proteins expressed not only in immune cells but also in other tissues and organs outside the immune system. In this review, we discuss mechanisms responsible for IRF-mediated innate immune responses and the function and mechanism of IRFs in cardiometabolic diseases. We focus on the role of IRFs in innate immunity and cardiometabolic homeostasis, and highlight reprogrammed IRF signaling.
