Estimated cumulative incidence of West Nile virus infection in US adults, 1999-2010
Estimated cumulative incidence of West Nile virus infection in US adults, 1999-2010
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DOI：
10.1017/s0950268812001070
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发表时间：
2013-03-01
影响因子：
4.2
通讯作者：
Busch, M. P.
中科院分区：
文献类型：
--
作者：
Petersen, L. R.;Carson, P. J.;Busch, M. P.
西尼罗河病毒 (WNV) 于 1999 年在美国首次被识别。我们利用最近得出的按年龄和性别分层的 WNV 神经侵袭性疾病 (WNND) 感染比率以及向国家监测报告的 WNND 病例数，估计了 1999 年至 2010 年美国 WNV 感染的累积发病率。我们估计美国已有超过300万人感染西尼罗河病毒，其中中原各州的发病率最高。这 300 万人感染将导致约 78 万人患病。大量西尼罗河病毒感染和疾病发生在该病毒在美国的第一个十年。
West Nile virus (WNV) was first recognized in the USA in 1999. We estimated the cumulative incidence of WNV infection in the USA from 1999 to 2010 using recently derived age- and sex-stratified ratios of infections to WNV neuroinvasive disease (WNND) and the number of WNND cases reported to national surveillance. We estimate that over 3 million persons have been infected with WNV in the USA, with the highest incidence rates in the central plains states. These 3 million infections would have resulted in about 780 000 illnesses. A substantial number of WNV infections and illnesses have occurred during the virus' first decade in the USA.