Smoking cessation increases gingival blood flow and gingival crevicular fluid
Smoking cessation increases gingival blood flow and gingival crevicular fluid
复制标题
DOI：
10.1111/j.1600-051x.2004.00476.x
复制
发表时间：
2004-04-01
影响因子：
6.7
通讯作者：
Yoshie, H
中科院分区：
文献类型：
--
作者：
Morozumi, T;Kubota, T;Yoshie, H
目的：本研究的目的是确定戒烟对牙龈血流量（GBF）和龈沟液（GCF）的影响。材料和方法：16名男性吸烟者（年龄22-39（25.3+/-4.0）岁），没有牙周和全身疾病的临床体征，被招募。实验在戒烟前（基线）和戒烟后1、3、5天，以及戒烟后1、2、4、8周进行。通过呼出的一氧化碳（CO）浓度以及血清尼古丁和可替宁浓度来验证吸烟和戒烟的状态。激光多普勒流量计被用来连续记录相对血流，在三个牙龈网站的左上颌中切牙（中唇方面的牙龈边缘和双边牙间乳头）。在左侧上颌中切牙的近中唇侧和远唇侧收集GCF，并通过Periotron 6000（R）系统计算体积。除GBF外，对11名年龄在23-27（24.4+/-1.2）岁的非吸烟对照者（4名女性和7名男性）进行了相同的测量。在戒烟后1天，CO浓度显著低于基线水平（p
Objectives: The purpose of the present study was to determine the effect of smoking cessation on gingival blood flow (GBF) and gingival crevicular fluid (GCF).Material and Methods: Sixteen male smokers (aged 22-39 (25.3+/-4.0) years), with no clinical signs of periodontal and systemic diseases, were recruited. The experiment was performed before (baseline) and at 1, 3 and 5 days, and at 1, 2, 4 and 8 weeks after smoking cessation. The status of smoking and smoking cessation was verified by exhaled carbon monoxide (CO) concentration, and by serum nicotine and cotinine concentrations. A laser Doppler flowmeter was used to record relative blood flow continuously, on three gingival sites of the left maxillary central incisor (mid-labial aspect of the gingival margin and bilateral interdental papillae). The GCF was collected at the mesio- and disto-labial aspects of the left maxillary central incisor and the volume was calculated by the Periotron 6000(R) system. The same measurements except for the GBF were performed on 11 non-smoking controls (four females and seven males), aged 23-27 (24.4+/-1.2) years.Results: Eleven of 16 smokers successfully completed smoking cessation for 8 weeks. At 1 day after smoking cessation, there was a significantly lower CO concentration than at baseline (p