Monitoring 6‐thioguanine nucleotide concentrations in Japanese children and adolescents with inflammatory bowel disease
Monitoring 6‐thioguanine nucleotide concentrations in Japanese children and adolescents with inflammatory bowel disease
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DOI：
10.1111/j.1440-1746.2010.06364.x
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发表时间：
2010-10
影响因子：
4.1
通讯作者：
Y. Ohtsuka;K. Arai;Y. Aoyagi;T. Fujii;Yoko Yamakawa;Kiyotaka Ohtani;T. Ikuse;Y. Baba;Eisuke Inage-Eis
中科院分区：
文献类型：
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作者：
Y. Ohtsuka;K. Arai;Y. Aoyagi;T. Fujii;Yoko Yamakawa;Kiyotaka Ohtani;T. Ikuse;Y. Baba;Eisuke Inage-Eis
背景和目的：6-巯基嘌呤（6-MP）和硫唑嘌呤（AZA）被广泛用作炎症性肠病（IBD）儿童的维持治疗。然而，尚未报告日本IBD儿童中适当的6-硫代鸟嘌呤核苷酸（6-TGN）浓度。
Background and Aim: 6‐Mercaptopurine (6‐MP) and azathioprine (AZA) are widely used as maintenance therapy in children with inflammatory bowel disease (IBD). However, proper 6‐thioguanine nucleotide (6‐TGN) concentrations in Japanese children with IBD have not been reported.