Alternative models for two crystal structures of bovine rhodopsin.
Alternative models for two crystal structures of bovine rhodopsin.
复制标题
牛视紫红质的两种晶体结构的替代模型。
DOI：
10.1107/s0907444908017162
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Stenkamp,RonaldE
中科院分区：
文献类型：
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作者：
Stenkamp,RonaldE
视紫红质的两种晶体形式（PDB代码1gzm和2 j 4 y;空间群P31）的空间群对称性可以重新解释为六边形（空间群P64）。在三角模型的不对称单元中存在两个G蛋白偶联受体分子。然而，平行于c轴的非晶体学二重轴可以被视为六方空间群中的晶体学对称操作。这使得不对称单位减半，并使所有蛋白质分子在这些结构中等同。修正的半面体孪生也适用于在更高的对称性空间群的结构（2 j 4 y）的细化。
The space-group symmetry of two crystal forms of rhodopsin (PDB codes 1gzm and 2j4y; space group P31) can be re-interpreted as hexagonal (space group P64). Two molecules of the G protein-coupled receptor are present in the asymmetric unit in the trigonal models. However, the noncrystallographic twofold axes parallel to the c axis can be treated as crystallographic symmetry operations in the hexagonal space group. This halves the asymmetric unit and makes all of the protein molecules equivalent in these structures. Corrections for merohedral twinning were also applied in the refinement in the higher symmetry space group for one of the structures (2j4y).