Microembolism and Catheter Ablation II Effects of Cerebral Microemboli Injection in a Canine Model
Microembolism and Catheter Ablation II Effects of Cerebral Microemboli Injection in a Canine Model
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DOI：
10.1161/circep.112.973461
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发表时间：
2013-02-01
影响因子：
8.4
通讯作者：
Kanal, Emanuel
中科院分区：
文献类型：
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作者：
Haines, David E.;Stewart, Mark T.;Kanal, Emanuel
背景-在导管消融房颤后不久，弥散加权磁共振(DWI)扫描观察到了无症状的脑部病变，但这些病变的发病机制尚不完全清楚。方法和结果-12只狗接受了选择性颈内动脉或椎动脉插管。可以是空气(1.0-4.0毫升)、血液、对比剂和盐水(n=5)的微泡混合物，也可以是热干粉状血液(颗粒大小
Background-Asymptomatic cerebral lesions have been observed on diffusion weighted MRI (DWI) scans shortly after catheter ablation of atrial fibrillation, but the pathogenesis of these lesions is incompletely understood.Methods and Results-Twelve dogs underwent selective catheterization of the internal carotid or vertebral arteries. Either a microbubbled mixture of air (1.0-4.0 mL), blood, contrast, and saline (n=5), or heat-dried pulverized blood (particle size