Zwitterionic 1,2,3-Triazolium Amidate as a Catalyst for Photoinduced Hydrogen-Atom Transfer Radical Alkylation
Zwitterionic 1,2,3-Triazolium Amidate as a Catalyst for Photoinduced Hydrogen-Atom Transfer Radical Alkylation
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DOI：
10.1021/acscatal.9b04491
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发表时间：
2020-02-21
期刊：
影响因子：
12.9
通讯作者：
Ooi, Takashi
中科院分区：
文献类型：
--
作者：
Ohmatsu, Kohsuke;Suzuki, Ryuhei;Ooi, Takashi
两性离子 1,2,3-三唑酰胺盐被设计用作光氧化还原 C-H 功能化的有效模块化氢原子转移催化剂。这种两性离子酰胺化物是稳定的，但易于单电子氧化，产生高反应性酰胺自由基。与基于Ir的可见光光氧化还原催化剂配合使用，该最佳催化剂能够实现各种含氮或含氧有机化合物的C-H键的高效直接烷基化。
A zwitterionic 1,2,3-triazolium amidate was designed for use as an effective modular hydrogen-atom transfer catalyst for photoredox C-H functionalization. This zwitterionic amidate is stable yet amenable to single-electron oxidation for generating a highly reactive amidyl radical. In cooperation with an Ir-based visible-light photoredox catalyst, the optimal catalyst enables the efficient direct alkylation of the C-H bonds of various nitrogen-or oxygen-containing organic compounds.