Comparison of visual assessment of coronary stenosis with independent quantitative coronary angiography: Findings from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.
Comparison of visual assessment of coronary stenosis with independent quantitative coronary angiography: Findings from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.
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比较冠状动脉狭窄的视觉评估与独立的定量冠状动脉造影:前瞻性多中心成像研究的发现,用于评估胸痛(Promise)试验。
DOI:
10.1016/j.ahj.2016.10.014
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发表时间:
2017-03
影响因子:
4.8
通讯作者:
Patel MR
中科院分区:
文献类型:
--
作者:
Shah R;Yow E;Jones WS;Kohl LP 3rd;Kosinski AS;Hoffmann U;Lee KL;Fordyce CB;Mark DB;Lowe A;Douglas PS;Patel MR
The outcomes in patients by visual assessment and quantitative coronary angiography (QCA) for obstructive coronary artery disease (CAD) are not known. Our objective was to compare visual and QCA estimates of obstructive CAD, and assess their relationship to outcomes in stable patients with symptoms of CAD. The Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial randomized 10,003 patients with CAD symptoms to anatomical or functional testing. Site reports of invasive angiography detailing visual stenosis and independent, blinded QCA were performed for obstructive CAD (≥50% stenosis). Disagreement between methods was determined and compared to outcomes (death, myocardial infarction, unstable angina hospitalization, or major procedural complications). Of 929 patients (9.3% of PROMISE cohort) with angiograms assessed by sites and QCA, 593 (64%) had obstructive CAD per site reports, while 428 (46%) had stenosis ≥ 50% per QCA. Results differed in 177 patients (disagreement rate 19.1%, κ=0.63), of whom 171 had CAD per sites but not per QCA. One-year unadjusted Kaplan-Meier event rates were highest (5.1%) when QCA and visual assessment agreed for CAD, lowest (0.9%) when the 2 agreed for no obstructive CAD, and intermediate (3.1%) for patients who had CAD per visual assessment but not per QCA. Visual estimation of angiograms results in more frequent diagnosis of obstructive CAD as compared with QCA. Concordance of results for presence or absence of obstructive CAD was associated with high and low event rates, respectively. Disagreement was associated with intermediate event rates, suggesting that cardiologists integrated clinical information into routine visual assessment of angiograms.
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影响因子:
24
作者:
Fihn, Stephan D.;Gardin, Julius M.;Yancy, Clyde W.
通讯作者:
Yancy, Clyde W.
影响因子:
2.8
作者:
Faxon, DP;Vogel, R;Defre, K
通讯作者:
Defre, K
影响因子:
37.8
作者:
DEROUEN, TA;MURRAY, JA;OWEN, W
通讯作者:
OWEN, W
影响因子:
3.7
作者:
KAPLAN, EL;MEIER, P
通讯作者:
MEIER, P
DOI:
10.1016/0735-1097(91)90752-u
发表时间:
1991-10-01
影响因子:
24
作者:
FLEMING, RM;KIRKEEIDE, RL;STUART, Y
通讯作者:
STUART, Y