Imidazole derivative KK-42 boosts pupal diapause incidence and delays diapause termination in several insect species
Imidazole derivative KK-42 boosts pupal diapause incidence and delays diapause termination in several insect species
复制标题
咪唑衍生物 KK-42 会增加几种昆虫的蛹滞育发生率并延迟滞育终止
DOI：
10.1016/j.jinsphys.2015.02.003
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发表时间：
2015-03-01
影响因子：
2.2
通讯作者：
Denlinger, David L.
中科院分区：
文献类型：
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作者：
Liu, Yanqun;Zhang, Qirui;Denlinger, David L.
咪唑衍生物KK-42是一种合成的昆虫生长调节剂，以前已知能够避免几种鳞翅目昆虫的胚胎滞育，但它是否也影响滞育发生在其他发育阶段仍然未知。在本研究中，我们研究了KK-42对两种鳞翅目昆虫，中国栎蚕和玉米穗虫，以及一种双翅目昆虫，肉蝇Sarcophaga crassipalpis的蛹滞育的影响。以. pernyi，KK-42在长日照条件下延迟蛹的滞育终止，而长日照条件通常会打破该物种的滞育。同样，在H. KK-42延迟蛹滞育的终止，在该物种中，滞育通常被高温打破。经KK-42处理的蛹最终解除滞育并成功羽化为成虫，但滞育解除的时间明显延迟。KK-42还能显著提高棉铃虫蛹的滞育率。zea和S. crassipalpis对滞育幼虫有诱导作用，但不能诱导H.如果幼虫在通常不引起滞育反应的环境条件下饲养，则为玉蜀黍。实验用H。结果表明，KK-42对蛹滞育的影响具有剂量和龄期依赖性，但不具有温度依赖性。这里呈现的结果与KK-42和调节蛹滞育的蜕皮激素信号通路之间的联系是一致的。(C)2015爱思唯尔有限公司版权所有。
The imidazole derivative KK-42 is a synthetic insect growth regulator known previously to be capable of averting embryonic diapause in several Lepidoptera, but whether it also affects diapauses occurring in other developmental stages remains unknown. In the present study, we examined the effect of KK-42 on pupal diapause in two species of Lepidoptera, the Chinese oak silkworm Antheraea pernyi and the corn earworm Helicoverpa zea, and in one species of Diptera, the flesh fly Sarcophaga crassipalpis. In A. pernyi, KK-42 delayed pupal diapause termination under the long day conditions that normally break diapause in this species. Likewise, in H. zea, KK-42 delayed termination of pupal diapause, a diapause that, in this species, is normally broken by high temperature. KK-42-treated pupae of these two species eventually terminated diapause and successfully emerged as adults, but the timing of diapause termination was significantly delayed. KK-42 also significantly increased the incidence of pupal diapause in H. zea and S. crassipalpis when administered to larvae that were environmentally programmed for diapause, but it was not capable of inducing pupal diapause in H. zea if larvae were reared under environmental conditions that do not normally evoke the diapause response. Experiments with H. zea showed that the effect of KK-42 on pupal diapause was dose- and stage-dependent, but not temperature-dependent. Results presented here are consistent with a link between KK-42 and the ecdysteroid signaling pathway that regulates pupal diapause. (C) 2015 Elsevier Ltd. All rights reserved.