Exploration of the contribution of biobehavioral variables to the energy expenditure of preterm infants.
Exploration of the contribution of biobehavioral variables to the energy expenditure of preterm infants.
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DOI：
10.1177/1099800404272310
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发表时间：
2005-01-01
影响因子：
2.5
通讯作者：
O'Brien, Matthew
中科院分区：
文献类型：
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作者：
Pridham, Karen;Bhattacharya, Abhik;O'Brien, Matthew
早产儿能量消耗的变化可能是由于婴儿成熟度和急性肺病（呼吸窘迫综合征[RDS]）消退史以及生长、热量摄入和活动所致。在这项探索性的短期纵向研究中使用间接量热法，通过测量吸入和呼出的O2和CO2来估计能量消耗（EE）。样本包括10名早产儿的35项评估（5名有RDS病史，5名无RDS病史）。将肺部疾病史（RDS消退，未诊断为RDS）、从出生体重恢复之日至研究日的体重增加（g/d）、平均活动水平、评估次数（1-6）以及肺部疾病史和时间的相互作用纳入重复测量的线性混合模型中。时间是怀孕后和出生后年龄的指标;所有3个都高度相关。由于热量摄入与体重增加高度相关，因此分析模型中不包括热量摄入。肺部疾病史，平均活动水平，和时间是显着的贡献者EE。一个更精确的测量医疗状况比存在或不存在的肺部疾病史，均匀间隔重复EE评估，并探索的情况下，婴儿表现出较高的活动水平，需要在一个复制研究与更大的样本。
Variation in energy expended by preterm infants may be due to infant maturity and history of resolved acute lung disease (respiratory distress syndrome [RDS]) as well as growth, caloric intake, and activity. Indirect calorimetry was used in this exploratory, short-term longitudinal study to estimate energy expenditure (EE) from measures of inspired and expired O2 and CO2. The sample included 35 assessments for 10 preterm infants (5 with and 5 without RDS history). Lung disease history (resolved RDS, no RDS diagnosis), weight gain (g/d) from the day on which birth weight had been regained to the study day, mean activity level, the number of the assessment (1-6), and the interaction of lung disease history and time were included in a linear mixed model for repeated measures. Time was an index of postconceptional and postnatal age; all 3 were highly correlated. Because of high correlation with weight gain, caloric intake was not included in the analytic model. Lung disease history, mean activity level, and time were significant contributors to EE. A more precise measure of medical status than absence or presence of lung disease history, evenly spaced repetitions of EE assessment, and exploration of contexts in which the infants exhibit a higher activity level are needed in a replication study with a larger sample.