Quantification and comparison of marijuana smoking practices: Blunts, joints, and pipes
Quantification and comparison of marijuana smoking practices: Blunts, joints, and pipes
复制标题
DOI：
10.1016/j.drugalcdep.2010.08.008
复制
发表时间：
2011-01-15
影响因子：
4.2
通讯作者：
Levin, Frances R.
中科院分区：
文献类型：
--
作者：
Mariani, John J.;Brooks, Daniel;Levin, Frances R.
收集自我报告的大麻使用数据的量化方法不像酒精或香烟那样标准化，这对大麻使用障碍治疗研究提出了方法学挑战。使用大麻的血清和尿液标记物有很长的半衰期，限制了它们作为临床试验结果衡量标准的效用。基于日历的结构化访谈程序可以准确衡量自我报告的大麻使用频率，但无法可靠地解决使用数量或效力等问题。这项研究比较了钝器、关节和烟斗使用者的数量和分配的美元价值，这些使用者参加了两项测试大麻依赖药物疗法的临床试验。对时间线追踪方法进行了修改，纳入了使用替代物质代表大麻的方法，以使参与者能够估计使用的数量和价值。直率的使用者主要是黑人和西班牙裔，而接头和管道的使用者主要是白人。参与者报告说，他们在钝器中放置的大麻比在关节中多50%，在钝器中放置的大麻数量是在烟斗中放置的大麻数量的两倍多。这些发现证明了使用替代体重估计程序来增强基于日历的方法来衡量自我报告的大麻使用的可行性。在使用实践中的个体差异限制了这种方法的实用性，以估计对象内的比较，而不是对象之间的比较。(C)2010爱思唯尔爱尔兰有限公司。保留所有权利。
The quantification method for collecting self-reported marijuana use data is not standardized as it is for alcohol or cigarettes, which presents a methodologic challenge for marijuana use disorder treatment studies. Serum and urine markers of marijuana use have a long half-life, limiting their utility as a clinical trial outcome measure. Structured calendar-based interview procedures can accurately measure the frequency of self-reported marijuana use, but are unable to reliably address issues such as quantity of use or potency. This study compared the quantity and assigned-dollar value among users of blunts, joints, and pipes enrolled in two clinical trials testing pharmacotherapies for marijuana dependence. The timeline follow-back method was modified to incorporate using a surrogate substance to represent marijuana to enable participants to estimate the amount and value used. Blunt users were mostly black and Hispanic, while users of joints and pipes were primarily white. Participants reported that they placed 50% more marijuana in blunts than in joints and placed more than twice the amount of marijuana in blunts than in pipes. These findings demonstrate the feasibility of using a surrogate weight estimation procedure to augment calendar-based methods of measuring self-reported marijuana use. Individual variability in use practices limits the utility of this method to estimating within-subject comparisons, rather than between subject comparisons. (C) 2010 Elsevier Ireland Ltd. All rights reserved.