Different outcomes of vertical transmission of hepatitis C virus in a twin pregnancy
Different outcomes of vertical transmission of hepatitis C virus in a twin pregnancy
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双胎妊娠中丙型肝炎病毒垂直传播的不同结果
DOI：
10.1046/j.1440-1746.2002.02601.x
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发表时间：
2002
影响因子：
4.1
通讯作者：
I. Sekine
中科院分区：
文献类型：
--
作者：
A. Inui;T. Fujisawa;T. Sogo;H. Komatsu;A. Isozaki;I. Sekine
丙型肝炎病毒(丙型肝炎病毒)从母亲向婴儿垂直传播的风险已经被很好地记录下来，但确切的传播方式仍不清楚。在一组单绒毛膜羊膜同卵双胞胎中，只有第二个婴儿从血清丙型肝炎病毒RNA阳性的母亲那里感染了丙型肝炎病毒。这两个婴儿的阴道分娩并不复杂，相隔3 分钟，他们从一开始就是奶瓶喂养的。第二个婴儿发展为临床肝炎，持续了30个月的随访。对于这对双胞胎来说，宫内环境应该是相同的，因此，母亲的丙型肝炎病毒因素，包括病毒载量，并不是丙型肝炎病毒母婴传播的唯一决定因素。
The risk of vertical transmission of hepatitis C virus (HCV) from mother to infant has been well documented, but the exact mode of transmission is still unclear. In a set of monochorionic diamniotic monozygous twins, only the second baby was infected with HCV from the mother who was positive for serum HCV‐RNA. The babies had an uncomplicated vaginal delivery 3 min apart and they were both bottle fed from the outset. The second baby developed clinical hepatitis that persisted to 30 months follow up. The intrauterine environment should have been identical for these twins, and therefore, the maternal HCV factors, including viral load are not the sole determining factors for mother‐to‐infant transmission of HCV.
DOI：
10.1056/nejm199408113310612
发表时间：
1994-08
期刊：
The New England journal of medicine
影响因子：
--
作者：
B. Gürakan;O. Oran;S. Yiğit
通讯作者：
B. Gürakan;O. Oran;S. Yiğit
母体血浆人类免疫缺陷病毒 1 型 RNA 水平：母婴传播的决定因素和预计阈值。
DOI：
10.1073/pnas.92.26.12100
发表时间：
1995
影响因子：
11.1
作者：
Fang,G;Burger,H;Grimson,R;Tropper,P;Nachman,S;Mayers,D;Weislow,O;Moore,R;Reyelt,C;Hutcheon,N;Baker,D;Weiser,B
通讯作者：
Weiser,B