The Salmonella typhimurium uracil-sensitive mutation use is in argU and encodes a minor arginine tRNA.
The Salmonella typhimurium uracil-sensitive mutation use is in argU and encodes a minor arginine tRNA.
复制标题
鼠伤寒沙门氏菌尿嘧啶敏感突变使用在 argU 中，编码少量精氨酸 tRNA。
DOI：
10.1128/jb.175.12.3897-3899.1993
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发表时间：
1993
影响因子：
3.2
通讯作者：
Abdelal,AT
中科院分区：
文献类型：
--
作者：
Lu,CD;Abdelal,AT
鼠伤寒沙门氏菌的使用基因先前通过赋予对葡萄糖基本培养基中尿嘧啶敏感性的突变来鉴定。使用基因被克隆并鉴定为编码次要精氨酸密码子（CGG）的tRNA的argU等位基因。尿嘧啶敏感的表型被证明是由于该tRNA的反密码子茎中的碱基取代。
The use gene of Salmonella typhimurium was previously identified by a mutation conferring sensitivity to uracil in glucose minimal medium. The use gene was cloned and identified as an allele of argU encoding a tRNA for a minor arginine codon (CGG). The uracil-sensitive phenotype was shown to result from a base substitution in the anticodon stem of this tRNA.