Factors determining HIV viral testing of infants in the context of mother-to-child transmission
Factors determining HIV viral testing of infants in the context of mother-to-child transmission
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DOI：
10.1111/j.1651-2227.2009.01670.x
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发表时间：
2010-04-01
期刊：
影响因子：
3.8
通讯作者：
Mlambo, G.
中科院分区：
文献类型：
--
作者：
Peltzer, K.;Mlambo, G.
目的：本研究的目的是探讨在预防母婴传播艾滋病病毒（PMTCT）的背景下，婴儿的HIV病毒检测的决定因素。方法：产后18岁及以上的HIV感染的母亲与3-6个月的婴儿进行了采访，对HIV病毒检测的婴儿和相关因素。结果：在311例HIV感染的妇女中，61.7%的婴儿在4 - 8周内进行了HIV病毒检测。双变量分析发现，母亲年龄较大、抑郁评分较低、预防母婴传播知识较高、预防母婴传播风险行为较低（母婴奈韦拉平依从性、卫生设施分娩和纯配方奶粉喂养）、艾滋病毒状态披露和参加支持小组与PCR检测参与相关。在多变量分析更高的PMTCT知识，婴儿奈韦拉平坚持，而不是排他性的母乳喂养与聚合酶链反应测试participation.Conclusion：各种决定因素的接受参与艾滋病毒检测的婴儿在PMTCT的背景下，可以指导婴儿检测和诊断咨询和支持服务的PMTCT方案。
Aim:The aim of this study was to investigate factors determining HIV viral testing of infants in the context of Prevention of Mother-to-Child Transmission of HIV (PMTCT).Methods:Post-delivery HIV infected mothers 18 years and above with babies aged 3-6 months were interviewed on HIV viral testing of infants and factors associated with it.Results:Among 311 HIV infected women 61.7% had their infant tested for HIV between 4 and 8 weeks. Bivariate analyses found that older age of the mothers, lower depression scores, higher PMTCT knowledge, low PMTCT risk behaviour (maternal and infant nevirapine adherence, health facility delivery and exclusive formula feeding), HIV status disclosure and attending a support group were associated with PCR test participation. In multivariate analyses higher PMTCT knowledge, infant nevirapine adherence, and not exclusive breast feeding were associated with polymerase chain reaction test participation.Conclusion:Various determinants of acceptance of participation in HIV viral testing of infants in the context of PMTCT were identified that can guide infant testing and diagnosis counselling and support services of PMTCT programmes.