Fatigue with systolic heart failure.
Fatigue with systolic heart failure.
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DOI：
10.1097/jcn.0b013e3181ae1e84
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发表时间：
2009-09
期刊：
影响因子：
--
通讯作者：
Piano MR
中科院分区：
文献类型：
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作者：
Fink AM;Sullivan SL;Zerwic JJ;Piano MR
疲劳是收缩期心力衰竭（HF）患者最常见的症状之一。关于心力衰竭患者疲劳的生理和社会心理基础的信息仍然不足。本研究的具体目的是：(1)确定心力衰竭患者2份疲劳问卷的心理测量特征，(2)将心力衰竭患者的疲劳与已发表的健康成人和正在接受治疗的癌症患者的疲劳进行比较，(3)确定心力衰竭患者疲劳的生理（如血红蛋白、b型利钠肽、体重指数和射血分数）和心理社会（如抑郁情绪）相关因素。从2个城市医疗中心招募87例心衰门诊患者作为方便样本。患者完成疲劳症状量表、情绪状态量表和短表36健康调查。心衰患者和癌症患者报告的疲劳程度相似，两组患者报告的疲劳程度都明显高于健康成年人。身体功能和血红蛋白类别解释了疲劳症状清单干扰量表得分30%的差异，而抑郁情绪和身体功能解释了情绪状态概况疲劳子量表得分47%的差异。心衰患者经历了与癌症相关的疲劳相当的严重疲劳。身体机能低下、情绪低落和血红蛋白水平低与hf相关的疲劳有关。
Fatigue is one of the most prevalent symptoms in persons with systolic heart failure (HF). There remains insufficient information about the physiological and psychosocial underpinnings of fatigue in HF. The specific aims of this study were to (1) determine the psychometric properties of 2 fatigue questionnaires in patients with HF, (2) compare fatigue in patients with HF to published scores of healthy adults and patients with cancer undergoing treatment, and (3) identify the physiological (eg, hemoglobin, B-type natriuretic peptide, body mass index, and ejection fraction) and psychosocial (eg, depressed mood) correlates of fatigue in HF. A convenience sample of 87 HF outpatients was recruited from 2 urban medical centers. Patients completed the Fatigue Symptom Inventory, Profile of Mood States, and Short Form-36 Health Survey. Patients with HF and patients with cancer reported similar levels of fatigue, and both patient groups reported significantly more fatigue than did healthy adults. Physical functioning and hemoglobin categories explained 30% of the variance in Fatigue Symptom Inventory-Interference Scale scores, whereas depressed mood and physical functioning explained 47% of the variance in Profile of Mood States Fatigue subscale scores. Patients with HF experienced substantial fatigue that is comparable with cancer-related fatigue. Low physical functioning, depressed mood, and low hemoglobin level were associated with HF-related fatigue.