Automatic registration of MRI-based joint models to high-speed biplanar radiographs for precise quantification of in vivo anterior cruciate ligament deformation during gait.
Automatic registration of MRI-based joint models to high-speed biplanar radiographs for precise quantification of in vivo anterior cruciate ligament deformation during gait.
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DOI：
10.1016/j.jbiomech.2018.09.010
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发表时间：
2018-11-16
影响因子：
2.4
通讯作者：
DeFrate LE
中科院分区：
文献类型：
--
作者：
Englander ZA;Martin JT;Ganapathy PK;Garrett WE;DeFrate LE
了解动态活动过程中的体内关节力学对于揭示损伤和疾病发展的机制至关重要。为此，实验室已经利用计算机断层扫描（CT）来创建骨的3维（3D）模型，然后将其配准到在运动期间捕获的高速双平面射线照相数据，以便测量体内关节运动学。在本研究中，我们描述了一个系统，用于测量动态关节力学使用3D表面模型的关节创建的磁共振成像（MRI）注册到高速双平面射线照片，使用一种新的自动注册算法。MRI的使用允许对骨和软组织结构进行建模。具体而言，可以对股骨和胫骨上的前交叉韧带（ACL）的附着部位足迹进行建模，从而允许测量动态ACL变形。在本研究中，我们通过跟踪尸体猪膝关节的运动来证明该系统的精度。然后，我们利用这个系统来量化在体内ACL变形步态在四个健康志愿者。
Understanding in vivo joint mechanics during dynamic activity is crucial for revealing mechanisms of injury and disease development. To this end, laboratories have utilized computed tomography(CT) to create 3-dimensional (3D) models of bone, which are then registered to high-speed biplanar radiographic data captured during movement in order to measure in vivo joint kinematics. In the present study, we describe a system for measuring dynamic joint mechanics using 3D surface models of the joint created from magnetic resonance imaging (MRI) registered to high-speed biplanar radiographs using a novel automatic registration algorithm. The use of MRI allows for modeling of both bony and soft tissue structures. Specifically, the attachment site footprints of the anterior cruciate ligament (ACL) on the femur and tibia can be modeled, allowing for measurement of dynamic ACL deformation. In the present study, we demonstrate the precision of this system by tracking the motion of a cadaveric porcine knee joint. We then utilize this system to quantify in vivo ACL deformation during gait in four healthy volunteers.
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影响因子：
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作者：
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通讯作者：
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