Analysis of hippocampal atrophy in alcoholic patients by a Kohonen feature map
Analysis of hippocampal atrophy in alcoholic patients by a Kohonen feature map
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DOI：
10.1097/00001756-200402090-00031
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发表时间：
2004-02-09
期刊：
影响因子：
1.7
通讯作者：
Bleich, S
中科院分区：
文献类型：
--
作者：
Kurth, C;Wegerer, V;Bleich, S
我们研究了海马体积与同型半胱氨酸，叶酸，维生素B12和136在酒精中毒患者和健康对照应用Kohonen特征图（KFM）和传统的统计学。在KFM中，受试者的表现表明海马体积与血液中同型半胱氨酸水平呈负相关，与叶酸和维生素B6呈负相关。在传统的统计分析（t检验）中发现，与健康对照组相比，酗酒者叶酸水平降低，同型半胱氨酸水平升高（p
We investigated the correlation of hippocampal volume with homocysteine, folate, vitamin B12 and 136 in alcoholic patients and healthy controls applying a Kohonen feature map (KFM) and conventional statistics. Representation of subjects on the KFM suggested an inverse correlation of hippocampal volume with blood levels of homocysteine and correlation with folate and vitamin B6. In conventional statistical analyses (t-test) reduced folate and increased homocysteine was found in alcoholics compared to healthy controls (p