2009 West Nile disease epidemic in Italy: First evidence of overwintering in Western Europe?
2009 West Nile disease epidemic in Italy: First evidence of overwintering in Western Europe?
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DOI：
10.1016/j.rvsc.2011.01.008
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发表时间：
2011-10-01
影响因子：
2.4
通讯作者：
Lelli, R.
中科院分区：
文献类型：
--
作者：
Monaco, F.;Savini, G.;Lelli, R.
连续第二年，西尼罗河病（WND）流行病影响了意大利，导致马和人患病。感染在2008年的同一地点再次发生，并向西和向南移动，涉及新的地区和地区。将意大利2009年西尼罗病毒分离株（WNDV）的全基因组序列与2008年WND暴发的病毒进行了比较。并对两个流行年的流行病学调查结果进行了比较。2008年和2009年西尼罗河病毒株之间的高度一致性（>99%）、2009年病毒传播较早以及疾病从前一年感染的边界感染区开始重新发生，强烈支持病毒越冬和在当地宿主种群中流行的假设。(C)2011爱思唯尔有限公司保留所有权利。
For the second consecutive year a West Nile disease (WND) epidemic has affected Italy causing disease in horses and humans. The infection re-occurred in the same places of the 2008 and moved westerly and southerly involving new areas and regions. The whole genome sequence of the Italian 2009 West Nile disease isolate (WNDV) was compared with those responsible for the 2008 WND outbreaks. The epidemiological findings of the two years of epidemic were compared as well. The high identity between 2008 and 2009 WNV strains (>99%), the earlier virus circulation in 2009 and the re-occurrence of the disease starting from the bordering infected areas reached by the infection in the previous year, strongly support the hypothesis of the overwintering of the virus and the endemisation to local host populations. (C) 2011 Elsevier Ltd. All rights reserved.