Cationic Late-Transition-MetalComplexes Catalyze the Ring Opening of Aziridines withAmines
Cationic Late-Transition-MetalComplexes Catalyze the Ring Opening of Aziridines withAmines
复制标题
阳离子后过渡金属配合物催化氮丙啶与胺的开环
DOI：
10.1055/s-0031-1289611
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
C. Schneider
中科院分区：
文献类型：
--
作者：
A. Marti;S. Peruncheralathan;C. Schneider
已经发现阳离子钯和镍络合物非常有效地催化内消旋-N-芳基氮杂环丙烷与苯胺的开环，并且以典型地优异的产率提供有价值的1，2-二胺。活性催化剂由相应的金属二氯化物双（三苯基膦）配合物通过氯化物提取与银盐原位生成。这种新的协议是适用于广泛的基板范围与环状以及无环氮杂环丙烷。此外，阳离子金-膦络合物被证明是高度反应性的，并且以相当的速率和产率递送产物。
Cationic palladium and nickel complexes have been found to catalyze the ring-opening of meso-N-aryl aziridines with anilines very efficiently and furnish valuable 1, 2-diamines in typically excellent yields. The active catalysts were generated in situ from the corresponding metal dichloride bis (triphenylphosphine) complexes through chloride abstraction with a silver salt. This new protocol is applicable across a broad substrate range with both cyclic as well as acyclic aziridines. In addition, cationic gold-phosphine complexes proved to be highly reactive as well as delivering products in comparable rates and yields.