The role of actin bundling proteins in the assembly of filopodia in epithelial cells
The role of actin bundling proteins in the assembly of filopodia in epithelial cells
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DOI：
10.4161/cam.5.5.17644
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发表时间：
2011-09-01
影响因子：
3.2
通讯作者：
George, Sudeep P.
中科院分区：
文献类型：
--
作者：
Khurana, Seema;George, Sudeep P.
本综述的目的是强调丝状伪足组装的新兴模型（包括组织特异性肌动蛋白捆绑蛋白）如何能够更全面地呈现丝状伪足组装，从而更充分、有效地描述上皮细胞的复杂性和可塑性。本综述还阐述了必须考虑肌动蛋白捆绑蛋白的真实多样性，以预测丝状伪足在上皮细胞中深远的意义和多种功能。
The goal of this review is to highlight how emerging new models of filopodia assembly which include tissue specific actin-bundling proteins could provide more comprehensive representations of filopodia assembly that would describe more adequately and effectively the complexity and plasticity of epithelial cells. This review also describes how the true diversity of actin bundling proteins must be considered to predict the far-reaching significance and versatile functions of filopodia in epithelial cells.