Diagnosis and treatment of sick sinus syndrome.
Diagnosis and treatment of sick sinus syndrome.
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发表时间：
2003-04
影响因子：
4
通讯作者：
V. Adán;L. Crown
中科院分区：
文献类型：
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作者：
V. Adán;L. Crown
病窦综合征包括涉及窦房结功能障碍的多种病症，通常影响老年人。虽然该综合征可能有许多原因，但通常是特发性的。患者可能会出现晕厥、晕厥前期、心悸或头晕;然而，他们通常无症状或有轻微或非特异性症状。病窦综合征在心电图上有多种表现，包括窦性心动过缓、窦性停搏、窦房阻滞以及心动过缓和心动过速的交替模式（心动过缓-心动过速综合征）。病窦综合征的诊断是困难的，因为它的非特异性症状和心电图或霍尔特监测难以发现。治疗的主要方法是心房或双腔起搏器植入，与心室起搏器相比，心房或双腔起搏器植入通常可有效缓解症状，降低房颤、血栓栓塞事件、心力衰竭和死亡率的发生率。
Sick sinus syndrome comprises a variety of conditions involving sinus node dysfunction and commonly affects elderly persons. While the syndrome can have many causes, it usually is idiopathic. Patients may experience syncope, pre-syncope, palpitations, or dizziness; however, they often are asymptomatic or have subtle or nonspecific symptoms. Sick sinus syndrome has multiple manifestations on electrocardiogram, including sinus bradycardia, sinus arrest, sinoatrial block, and alternating patterns of bradycardia and tachycardia (bradycardia-tachycardia syndrome). Diagnosis of sick sinus syndrome can be difficult because of its nonspecific symptoms and elusive findings on electrocardiogram or Holter monitor. The mainstay of treatment is atrial or dual-chamber pacemaker placement, which generally provides effective relief of symptoms and lowers the incidence of atrial fibrillation, thromboembolic events, heart failure, and mortality, compared with ventricular pacemakers.