Long-term suicide risk of depression in the Lundby cohort 1947-1997 -: severity and gender

Long-term suicide risk of depression in the Lundby cohort 1947-1997 -: severity and gender
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DOI:
10.1111/j.1600-0447.2007.01136.x
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发表时间:
2008-03-01
影响因子:
6.7
通讯作者:
Nettelbladt, P.
Nettelbladt, P.
中科院分区:
医学1区
文献类型:
--
作者:
Bradvik, L.;Mattisson, C.;Nettelbladt, P.

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目的:在社区样本中按严重程度和性别评估抑郁症的长期自杀风险。方法:Lundby研究是一项前瞻性的纵向队列研究,研究对象为3563名受试者。在1947-1997年间,根据Lundby诊断系统登记了503名受试者的中度或重度抑郁症。根据DSM-IV诊断为重度抑郁障碍(MDD)293人,未明确诊断抑郁障碍(DDNOS)131人。结果:总体长期自杀风险为5.6%~6.8%。中度和重度Lundby抑郁症的长期自杀风险分别为3.1%和11.4%,中度和重度MDD+DDNOS的长期自杀风险分别为3.7%和13.8%,中度MDD和重度MDD的长期自杀风险分别为3.1%和13.7%。严重程度和男性性别是自杀的危险因素。结论:重度抑郁症的男性有较高的长期自杀风险,约为20%。
Objective: The long-term suicide risk of depression was evaluated in a community sample by severity and gender.Method: The Lundby study is a prospective, longitudinal cohort study on a population consisting of 3563 subjects. In 1947-1997 medium or severe depression according to the Lundby diagnostic system were registered in 503 subjects. The same subjects were also diagnosed according to DSM-IV showing major depressive disorder (MDD) in 293 and depressive disorder not otherwise specified (DDNOS) in 131 subjects.Results: The overall long-term suicide risk varied from 5.6% to 6.8%. The long-term suicide risk was 3.1% for medium and 11.4% for severe 'Lundby depression', 3.7% for medium and 13.8% for severe MDD + DDNOS, 3.1% for medium and 13.7% for severe MDD. Severity and male sex were risk factors for suicide.Conclusion: Males with a severe depression showed a high long-term risk for suicide, around 20%.