Prevalence of Red-Green Color Vision Defects among Muslim Males and Females of Manipur, India
Prevalence of Red-Green Color Vision Defects among Muslim Males and Females of Manipur, India
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印度曼尼普尔邦穆斯林男性和女性红绿色视觉缺陷的患病率
DOI：
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发表时间：
2013
影响因子：
1.4
通讯作者：
Mohammad Afzal
中科院分区：
文献类型：
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作者：
Ahsana Shah;Ruqaiya Hussain;M. Fareed;Mohammad Afzal
背景：色盲是一种常见的X连锁遗传病。然而，由于缺乏适当的筛选，大多数色盲仍然未被发现。我们的研究是为了确定Manipuri穆斯林男性和女性中红绿色觉缺陷的患病率。这项研究可能有助于减少患有这种疾病的儿童的出生，因为穆斯林通常在他们之间进行近亲结婚。研究方法：两种性别的无关个体随机选择属于六个不同群体的（男性-1352，女性-1302），并使用Ishihara色觉缺陷筛查红-绿色觉缺陷。（伪等色板）测试来自曼尼普尔的英帕尔东区和英帕尔西区，这是一个小丘陵州，位于印度的东北角，与缅甸接壤。结果：色盲的检出率男性为8.73%，女性为1.69%。在所研究的6个不同种群中，Meitei种群的雄性出现频率最高，为14.93%，而那牙种群的雄性出现频率最低，为3.75%。在女性中，Meitei人口再次显示出最高的频率为2.5%，最低的频率是由莫卧儿和那牙人口0.00%，因为没有一个单一的女性色盲是founded. Conclusion：目前的研究表明，色盲的患病率较高，相比其他报告的印度率。Deuteranomaly病例的发生率高于其他类型的色盲。在穆斯林中观察到的较高流行率可能是由于近亲婚姻的隐性影响。
Background: Color blindness is a common X-linked genetic disorder. However, most of color blinds remain undetected due to absence of proper screening. Our study was to determine the prevalence of red-green color vision defects among Manipuri Muslim males and females. The study could help in decreasing birth of children with this disorder as Muslims commonly perform consanguineous marriage among themselves. Methods: Unrelated individuals of both sexes (Male-1352, Female-1302) belonging to six different populations were randomly selected and screened for red-green color vision defects using the Ishihara (pseudo-isochromatic plates) test from the area of Imphal East and Imphal west districts of Manipur, which is a small hilly state, situated in the north eastern extreme corner of India sharing an international boundary with Myanmar (Burma). Results: About 8.73% of males and 1.69% of females were found to be color blind. Among six different populations studied the males of Meitei population shows the highest frequency i.e. 14.93% while Naga population shows the least frequency of 3.75%. Among females, Meitei population again shows the highest frequency of 2.5% and least frequency is shown by Mughal and Naga populations 0.00% as not a single female color blind was found. Conclusion: Present study shows higher prevalence rate of color blindness as compared to other reported rates of India. Deuteranomaly cases occur in higher percentage than other types of color blindness. The higher prevalence rate observed in Muslims may be due to the hidden effect of consanguineous marriages.