Structure and recognition of polyubiquitin chains of different lengths and linkage.
Structure and recognition of polyubiquitin chains of different lengths and linkage.
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DOI：
10.3410/b3-26
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Wilkinson KD
中科院分区：
文献类型：
--
作者：
Fushman D;Wilkinson KD
多聚泛素信号是后连接到大量的蛋白质，通常指导大分子复合物的形成，导致所连接的蛋白质的易位，组装或降解。最近的结构和功能研究揭示了区分不同结构和信号长度的一般机制。
The polyubiquitin signal is post-translationally attached to a large number of proteins, often directing formation of macromolecular complexes resulting in the translocation, assembly or degradation of the attached protein. Recent structural and functional studies reveal general mechanisms by which different architectures and length of the signal are distinguished.