Rarity of males in pea aphids results in mutational decay
Rarity of males in pea aphids results in mutational decay
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DOI：
10.1126/science.1147919
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发表时间：
2008-01-04
期刊：
影响因子：
56.9
通讯作者：
Nuzhdin, Sergey V.
中科院分区：
文献类型：
--
作者：
Brisson, Jennifer A.;Nuzhdin, Sergey V.
当雌性可以在没有雄性的情况下繁殖时，雄性是否会成为进化上较弱的性别，其基因会经历突变衰退？我们在蚜虫中解决了这一假设，蚜虫的生殖在单性生殖和有性生殖之间交替：在一年的时间里，可以有10到20代无性生殖的雌性，但只有一代（如果有的话）有雄性。我们使用微阵列分析来识别男性偏好、无性女性偏好和中性基因。种间比较表明，加速男性偏向的基因的进化，和种内多态性表现出显着过量的非同义编码变异的男性偏向的基因。我们的结论是，女性无性繁殖的能力，没有男性减少选择限制男性为基础的基因，导致其突变衰减。
When females can reproduce without males, do males become an evolutionarily weaker sex whose genes experience mutational decay? We addressed this hypothesis in aphids, whose reproduction alternates between parthenogenetic and sexual forms: Over the course of a year, there can be 10 to 20 generations of asexual females but only a single, if any, generation with males. We used microarray analyses to identify male-biased, asexual female‐biased, and neutral genes. Interspecific comparisons reveal accelerated evolution of male-biased genes, and intraspecific polymorphisms exhibit a significant excess of nonsynonymous coding variation in male-biased genes. We conclude that the ability of females to reproduce asexually without males reduces selection constraints on male-based genes, resulting in their mutational decay.