Adaptive Angular Sampling for SPECT Imaging.
Adaptive Angular Sampling for SPECT Imaging.
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DOI：
10.1109/tns.2011.2164935
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发表时间：
2011-10
影响因子：
1.8
通讯作者：
Meng LJ
中科院分区：
文献类型：
--
作者：
Li N;Meng LJ
提出了一种在单光子发射计算机断层成像（SPECT）中进行自适应角度采样的解析方法。它允许快速确定最佳采样策略，最大限度地减少感兴趣区域（ROI）中的图像方差。所提出的方法包括三个关键组成部分：（a）一组封闭的形式方程，用于评估图像方差和分辨率达到一个给定的采样策略，（B）一个基于梯度的算法搜索通过参数空间，以找到最佳的采样策略和（c）一个有效的计算方法，以加快搜索过程。在本文中，我们已经证明了使用所提出的分析方法与单头SPECT系统，在所有可能的采样角度的成像时间的最佳分布。与传统的均匀角度采样方法相比，自适应角度采样允许相机在更有效地获取有用的成像信息的角度处花费更大部分的成像时间。这导致显著降低的图像方差。在一般情况下，在这项研究中开发的分析方法可以使用许多核成像系统（如SPECT，PET和X射线CT）配备自适应硬件。这种策略可以提供优化的采样效率，从而提高图像质量。
This paper presents an analytical approach for performing adaptive angular sampling in single photon emission computed tomography (SPECT) imaging. It allows for a rapid determination of the optimum sampling strategy that minimizes image variance in regions-of-interest (ROIs). The proposed method consists of three key components: (a) a set of close-form equations for evaluating image variance and resolution attainable with a given sampling strategy, (b) a gradient-based algorithm for searching through the parameter space to find the optimum sampling strategy and (c) an efficient computation approach for speeding up the search process. In this paper, we have demonstrated the use of the proposed analytical approach with a single-head SPECT system for finding the optimum distribution of imaging time across all possible sampling angles. Compared to the conventional uniform angular sampling approach, adaptive angular sampling allows the camera to spend larger fractions of imaging time at angles that are more efficient in acquiring useful imaging information. This leads to a significantly lowered image variance. In general, the analytical approach developed in this study could be used with many nuclear imaging systems (such as SPECT, PET and X-ray CT) equipped with adaptive hardware. This strategy could provide an optimized sampling efficiency and therefore an improved image quality.