Oral allergy syndrome induced by spinach
Oral allergy syndrome induced by spinach
复制标题
菠菜引起的口腔过敏综合征
DOI：
10.1111/j.1398-9995.1997.tb02533.x
复制
发表时间：
1997
期刊：
影响因子：
12.4
通讯作者：
D. Martin‐Gil
中科院分区：
文献类型：
--
作者：
I. Sánchez;F. Rodriguez;J. García;L. Fernández;D. Quiñones;D. Martin‐Gil
这些毛毛虫的搔痒特性。仅在一项针对21名螯蝗工蚁的研究中证实了对这些毛虫过敏的大基因介导机制(5)。用EEISA法对21份样本进行了检测，并在其中的4份样本中检测出了针对浙江棘毛虫和柞蚕幼虫的特异性IgE抗体。三份面粉阳性样本对纯化的thaumetopocin有显著的IgE水平，在Western blotting中，每一份面粉血清都有松毛虫提取物的IgE激活带。反应性血清识别thumctopoein （2(S kDa)）和45kda蛋白。我们的工作是第二项研究，证明了IgE直接针对松树毛虫抗原的存在，并首次描述了IgE介导的对这些毛虫的过敏反应。在我们的科室，我们看到一些病人在松林里走了几个小时，没有直接接触毛毛虫，就出现了皮肤/眼部症状。这些症状不会出现在其他同等暴露的随行人员中。此外，7]松皮虫荨麻疹毛应被认为是重要的空气传播昆虫过敏原(4)；对这种新过敏原的进一步研究，特别是对松蝗工人的研究，是必要的。
the urticaling properties of these caterpillars. An lgE-mcdiated mechanism of hypersensitivily to these caterpillars has been demonstrated in only one study in 21 pinc-lorcst workers (5). Specific IgE antibodies directed against jiinc pixiccssionary and oak processionary caterpillars assayed by EEISA were detected in lour of the 21 samples studied by these authors. Three out of lour positive samples had significant levels of IgE directed against purified thaumetopocin and, in Western blotting, each of the lour sera had IgE-rcactivc bands with a pine processionary caterpillar extract. The reactive sera recognized thaumctopoein (2(S kDa) and a 45-kDa protein. Our work is the second study to demonstrate the presence of IgE directed against pine processionary caterpillar antigens and the first description of an IgE-mcdiatcd anaphylactic reaction to these caterpillars. In our department, we see some iiaticnts with cutaneous/ocular symptoms al'lcr several hours of walking in a pine forest without direct contact with caterpillars. These symptoms do not appear in other equally exposed accompanying persons. Moreover, 7] pityocampa urticating hairs should be considered important airborne insect allergens (4); further research with this new allergen, particularly in pine-lorcst workers, is necessary.