Preparation and blood compatibility of carbon/TiO2 nanocomposite
Preparation and blood compatibility of carbon/TiO2 nanocomposite
复制标题
碳/TiO2纳米复合材料的制备及其血液相容性
DOI：
10.1016/j.diamond.2013.06.011
复制
发表时间：
2013-09-01
影响因子：
4.1
通讯作者：
Chen, D. H.
中科院分区：
文献类型：
--
作者：
Chen, H. L.;Luo, P.;Chen, D. H.
合成了由不同sp(3)C含量的碳膜和TiO2纳米线阵列组成的碳/TiO2纳米复合材料，在掺氟氧化锡玻璃上采用水热法制备的TiO2纳米线阵列的顶表面涂覆了碳薄膜。分别采用脉冲磁过滤阴极真空电弧沉积、等离子体增强化学气相沉积和磁控溅射沉积制备了sp(3)C含量较高、中等和较低的碳薄膜。采用扫描电镜、透射电镜和x射线衍射研究了TiO2纳米线阵列的表面形貌和结构。利用拉曼光谱对碳膜中的sp(3)C含量进行了表征。通过体外血小板粘附试验，对制备的TiO2纳米线阵列、碳膜和碳/TiO2纳米复合材料的血液相容性进行评价。结果表明，与单一材料相比，碳/TiO2复合材料可以有效提高抗凝血功能。研究认为，碳/TiO2纳米复合材料优异的血液相容性是由纳米线阵列调节的表面特性和碳薄膜的电子结构共同作用的结果。(C) 2013年作者。Elsevier B.V.版权所有。
A carbon/TiO2 nanocomposite, which consists of carbon film with various sp(3)C content and TiO2 nanowire arrays, has been synthesized, in which the top surface of TiO2 nanowire arrays prepared using hydrothermal method on fluorine-doped tin oxide glass were coated with carbon thin films. The carbon thin films with a higher, medium and lower sp(3)C content were deposited by pulsed magnetic filtered cathodic vacuum arc deposition, plasma-enhanced chemical vapor deposition and magnetron sputtering deposition, respectively. The surface morphology and structure of TiO2 nanowire arrays were investigated by scanning electron microscopy, transmission electron microscope and X-ray diffraction. The sp(3)C content in carbon films was characterized using Raman spectroscopy. The blood compatibility of the samples including the TiO2 nanowire arrays, carbon films and carbon/TiO2 nanocomposite was assessed by tests of platelet adhesion in vitro. Results showed that the carbon/TiO2 composite can effectively improve the anticoagulant function compared to the single materials. It is believed that the excellent blood compatibility of the carbon/TiO2 nanocomposite is attributed to a joint function of surface properties adjusted by nanowire arrays and electronic structure of carbon thin films. (C) 2013 The Authors. Published by Elsevier B.V. All rights reserved.