Intracranial Arterial Wall Imaging Using Three-Dimensional High Isotropic Resolution Black Blood MRI at 3.0 Tesla
Intracranial Arterial Wall Imaging Using Three-Dimensional High Isotropic Resolution Black Blood MRI at 3.0 Tesla
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DOI：
10.1002/jmri.22592
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发表时间：
2011-07-01
影响因子：
4.4
通讯作者：
Wasserman, Bruce A.
中科院分区：
文献类型：
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作者：
Qiao, Ye;Steinman, David A.;Wasserman, Bruce A.
目的：建立一种3.0Tesla(T)的高各向同性分辨率成像序列来评价颅内血管。材料与方法：13名健康志愿者和4名颅内狭窄患者在3.0T使用0.5 mm各向同性分辨率三维各向同性TSE(Vista；TSE，快速自旋回波)成像，并与常规2D-TSE进行比较。6名志愿者和4名患者以0.4 mm的各向同性分辨率重复Vista，以探索SNR和体素体积之间的权衡。比较3D-Vista和2D-TSE序列的壁信噪比(SNR)、壁腔对比噪声比(CNR)、管腔面积(LA)、壁腔面积(WA)、平均壁厚(MWT)和最大壁厚(MaxWT)，以及在两种分辨率下获得的3D图像。结果：与2D-TSE测量相比，3D-Vista的SNR(WALL)和CNR(WALL-CAMEN)分别提高了58%和74%。3D和2D技术的LA、WA、MWT和MaxWT高度相关(ICCs分别为0.96、0.95。分别为0.96和0.91)。与0.5 mm Vista相比，使用0.4 mm分辨率Vista的CNR(壁腔)降低了27%，但减少了基于部分体积的对壁厚的高估。结论：3D-Vista在高各向同性分辨率下提供了信噪比高、可靠性高的颅内血管测量，能够在临床可接受的时间内实现广泛的覆盖。
Purpose: To develop a high isotropic-resolution sequence to evaluate intracranial vessels at 3.0 Tesla (T).Materials and Methods: Thirteen healthy volunteers and 4 patients with intracranial stenosis were imaged at 3.0T using 0.5-mm isotropic-resolution three-dimensional (3D) Volumetric ISotropic TSE Acquisition (VISTA; TSE, turbo spin echo), with conventional 2D-TSE for comparison. VISTA was repeated for 6 volunteers and 4 patients at 0.4-mm isotropic-resolution to explore the trade-off between SNR and voxel volume. Wall signal-to-noise-ratio (SNR(wall)), wall-lumen contrast-to-noise-ratio (CNR(wall-lumen)), lumen area (LA), wall area (WA), mean wall thickness (MWT), and maximum wall thickness (maxWT) were compared between 3D-VISTA and 2D-TSE sequences, as well as 3D images acquired at both resolutions. Reliability was assessed by intraclass correlations (ICC).Results: Compared with 2D-TSE measurements, 3D-VISTA provided 58% and 74% improvement in SNR(wall) and CNR(wall-lumen), respectively. LA, WA, MWT and maxWT from 3D and 2D techniques highly correlated (ICCs of 0.96, 0.95. 0.96, and 0.91, respectively). CNR(wall-lumen) using 0.4-mm resolution VISTA decreased by 27%, compared with 0.5-mm VISTA but with reduced partial-volume-based overestimation of wall thickness. Reliability for 3D measurements was good to excellent.Conclusion: The 3D-VISTA provides SNR-efficient, highly reliable measurements of intracranial vessels at high isotropic-resolution, enabling broad coverage in a clinically acceptable time.