Fluctuations of HIV load in semen of HIV positive patients with newly acquired sexually transmitted diseases

Fluctuations of HIV load in semen of HIV positive patients with newly acquired sexually transmitted diseases
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DOI:
10.1136/bmj.313.7053.341
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发表时间:
1996-08-10
影响因子:
--
通讯作者:
Boag, F
Boag, F
中科院分区:
医学1区
文献类型:
--
作者:
Atkins, MC;Carlin, EM;Boag, F

文献摘要

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Most HIV infections worldwide are acquired sexually, yet most coital episodes involving an infected partner do not result in acquisition of HIV. Acquisition of HIV must depend on both the volume of secretions transferred from the infected partner (donor) and the concentration ofHIV present in the secretions. However, exposure alone to such a virus inoculum is clearly insufficient to ensure transmission. The coexistence of other sexually transmitted diseases in either the recipient or donor could potentially increase the risk of transmission by causing genital ulcers or by releasing inflammatorycytokines which increase HIV replication. 1