Albumin-IgG complexes in human serum and plasma that inhibit blood platelet adhesion.
Albumin-IgG complexes in human serum and plasma that inhibit blood platelet adhesion.
复制标题
人血清和血浆中的白蛋白-IgG 复合物可抑制血小板粘附。
DOI：
10.1073/pnas.78.12.7750
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发表时间：
1981
影响因子：
11.1
通讯作者：
Mason,RG
中科院分区：
文献类型：
--
作者：
Sharma,NC;Mohammad,SF;Chuang,HY;Mason,RG
已从人血清中分离出大分子白蛋白-IgG复合物并进行了免疫学表征。这些复合物也存在于血浆中，似乎是血液的正常成分。该复合物可以证明在正常血清和血浆中的免疫电泳和火箭免疫电泳，以及通过使用两步放射免疫结合试验。白蛋白-IgG复合物抑制人血小板与玻璃的粘附，占血清总蛋白的12-16%。
Macromolecular albumin-IgG complexes have been isolated from human serum and characterized immunologically. These complexes are shown to be present in plasma also and appear to be normal constituents of blood. The complexes can be demonstrated in normal serum and plasma by immunoelectrophoresis and rocket immunoelectrophoresis, as well as by use of a two-step radioimmunologic binding test. The albumin-IgG complexes inhibit adhesion of human platelets to glass and account for 12-16% of the total protein in serum.