Domain specificity in visual cortex
Domain specificity in visual cortex
复制标题
DOI：
10.1093/cercor/bhj086
复制
发表时间：
2006-10-01
期刊：
影响因子：
3.7
通讯作者：
Kanwisher, N.
中科院分区：
文献类型：
--
作者：
Downing, P. E.;Chan, A. W. -Y.;Kanwisher, N.
我们研究了人类视觉皮层中类别选择区域的普遍性和特异性。在迄今为止对视觉皮层类别选择性的最广泛调查中，12名参与者在观看场景和19种不同物体类别时进行了功能性磁共振成像扫描。正如预期的那样，我们发现梭状面孔区（FFA）的面孔，海马旁区（PPA）的场景，以及纹状体外体区（EBA）的身体的选择性。此外，我们描述了三个主要的新发现。首先，FFA，PPA和EBA的选择性的证据得到加强的发现，每个领域的反应显着更强烈的首选类别比下一个最有效的其余19个刺激类别测试。第二，中颞回的一个区域，据报道，更强烈地响应工具比动物没有更强烈地响应工具比其他非工具类别（如水果和蔬菜），铸造怀疑这一地区的特征为工具选择性。最后，我们没有发现任何新的区域在枕颞通路，强烈选择其他类别。总之，这些结果表明少数区域的强烈选择性和视觉皮层中这些区域的稀缺性。
We investigated the prevalence and specificity of category-selective regions in human visual cortex. In the broadest survey to date of category selectivity in visual cortex, 12 participants were scanned with functional magnetic resonance imaging while viewing scenes and 19 different object categories in a blocked-design experiment. As expected, we found selectivity for faces in the fusiform face area (FFA), for scenes in the parahippocampal place rea (PPA), and for bodies in the extrastriate body area (EBA). In addition, we describe 3 main new findings. First, evidence for the selectivity of the FFA, PPA, and EBA was strengthened by the finding that each area responded significantly more strongly to its preferred category than to the next most effective of the remaining 19 stimulus categories tested. Second, a region in the middle temporal gyrus that has been reported to respond significantly more strongly to tools than to animals did not respond significantly more strongly to tools than to other nontool categories (such as fruits and vegetables), casting doubt on the characterization of this region as tool selective. Finally, we did not find any new regions in the occipitotemporal pathway that were strongly selective for other categories. Taken together, these results demonstrate both the strong selectivity of a small number of regions and the scarcity of such regions in visual cortex.