Diffusion‐weighted imaging of uterine adenomyosis: Correlation with clinical backgrounds and comparison with malignant uterine tumors
Diffusion‐weighted imaging of uterine adenomyosis: Correlation with clinical backgrounds and comparison with malignant uterine tumors
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子宫腺肌病的弥散加权成像：与临床背景的相关性以及与子宫恶性肿瘤的比较
DOI：
10.1111/jog.14621
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发表时间：
2021
影响因子：
1.6
通讯作者：
Togashi Kaori
中科院分区：
文献类型：
--
作者：
Yajima Ryo;Kido Aki;Kurata Yasuhisa;Fujimoto Koji;Nakao Kyoko Kameyama;Kuwahara Ryo;Nishio Naoko;Minamiguchi Sachiko;Mandai Masaki;Togashi Kaori
目的探讨子宫腺肌病扩散加权成像(SI-DWI)信号强度与临床背景的关系，比较子宫腺肌病与子宫恶性肿瘤的SI-DWI表现。方法对46例经磁共振诊断的子宫腺肌病患者和25例经手术证实的子宫恶性肌瘤患者进行研究。首先，根据SI-DWI将子宫腺肌病患者分为高信号组和低信号组，并与正常子宫肌层进行比较。其次，对子宫腺肌病的SI-DWI与患者的年龄、绝经状况、月经周期、痛经严重程度等临床背景资料进行相关性分析。定量比较低信号型子宫腺肌病(LIA)、高信号型子宫腺肌病(HIA)和恶性肿瘤组的DWI信号强度比(SIR)和表观扩散系数(ADC)。结果46例子宫腺肌病患者分为低信号26例和高信号20例。仅在月经周期阶段发现了显著的相关性。HIA的SIR明显低于恶性肿瘤，ADC值明显高于恶性肿瘤。HIA的ADC值明显高于LIA。SIR和ADC联合应用对子宫腺肌病的诊断效果较好(ROC曲线下面积为0.99)。结论子宫腺肌病的DWI信号强度有一定的变化，且与月经周期有关。与子宫恶性肿瘤相比，子宫腺肌病DWI高信号区的信号强度较低，ADC值较高，但两者存在重叠。
AimTo elucidate correlation between signal intensity on diffusion‐weighted images (SI‐DWI) and clinical backgrounds for uterine adenomyosis and to compare SI‐DWI of adenomyosis and malignant uterine tumors.MethodsThis study examined 46 adenomyosis patients diagnosed using magnetic resonance imaging and 25 patients with surgically confirmed malignant uterine myometrial tumor. First, adenomyosis cases were classified visually into high‐intensity and low‐intensity groups based on the SI‐DWI compared with that of normal uterine myometrium. Secondly, correlation was assessed between SI‐DWI of adenomyosis and patient clinical background information such as age, menopausal status, menstrual cycle and dysmenorrhea severity. Third, quantitative comparison was made of low‐intensity adenomyosis (LIA), high‐intensity adenomyosis (HIA) and malignant tumor groups for the signal intensity ratio (SIR) on DWI and the apparent diffusion coefficient (ADC). Their diagnostic performance was evaluated using logistic regression analysis and receiver operating characteristic (ROC) analysis.ResultsThe 46 adenomyosis cases were classified as 26 low‐intensity and 20 high‐intensity cases. Significant correlation was found only for menstrual cycle phases. HIA had significantly lower SIR and higher ADC than malignant tumor. The ADC of HIA was significantly higher than that of LIA. The combination of SIR and ADC showed excellent diagnostic performance (area under ROC curve, 0.99).ConclusionThere is a variation in signal intensity on DWI of uterine adenomyosis and it is associated with menstrual cycle phase. Adenomyosis with high signal intensity on DWI can be differentiated from malignant lesions by its lower signal intensity on DWI and higher ADC than that found for malignant uterine tumors, however overlaps exist.
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DOI：
--
发表时间：
2018
期刊：
Radiopaedia.org
影响因子：
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通讯作者：
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影响因子：
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