Factors associated with exacerbation of heart failure include treatment adherence and health literacy skills.
Factors associated with exacerbation of heart failure include treatment adherence and health literacy skills.
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DOI：
10.1038/clpt.2009.7
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发表时间：
2009-06
影响因子：
6.7
通讯作者：
Brater, D. C.
中科院分区：
文献类型：
--
作者：
Murray, M. D.;Tu, W.;Wu, J.;Morrow, D.;Smith, F.;Brater, D. C.
我们确定了与心力衰竭恶化相关的因素，使用一个嵌套在大学附属门诊实践随机试验中的队列（n = 192）。与急诊或住院治疗相关的因素包括左心室射血分数、血细胞比容和血清钠水平、再灌注依从性和阅读处方标签的能力。与再灌注依从性≥80%相比，再灌注依从性<40%与心力衰竭住院发生率高3倍相关（P = 0.002）。在多变量分析中，处方标签阅读技能与较低的心力衰竭特定急诊发生率相关（发生率比，0.76; 95%置信区间（CI），0.19-0.69），具有足够健康素养的参与者因心力衰竭住院的风险较低（发生率比，0.34; 95% CI，0.15-0.76）。我们的结论是，治疗依从性和健康素养技能不足是心力衰竭恶化的关键因素。这些发现强调了对患者进行药物仔细指导的必要性。
We determined the factors associated with exacerbation of heart failure, using a cohort (n = 192) nested within a randomized trial at a university-affiliated ambulatory practice. Factors associated with emergency or hospital care included left ventricular ejection fraction, hematocrit and serum sodium levels, refill adherence, and the ability to read a prescription label. Refill adherence of <40% was associated with a threefold higher incidence of hospitalization for heart failure than a refill adherence of ≥80% (P = 0.002). In multivariable analysis, prescription label reading skills were associated with a lower incidence of heart failure–specific emergency care (incidence rate ratio, 0.76; 95% confidence interval (CI), 0.19–0.69), and participants with adequate health literacy had a lower risk of hospitalization for heart failure (incidence rate ratio, 0.34; 95% CI, 0.15–0.76). We conclude that inadequate treatment adherence and health literacy skills are key factors in the exacerbation of heart failure. These findings emphasize the need for careful instruction of patients about their medications.
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影响因子：
5.7
作者：
Gazmararian, Julie A.;Kripalani, Sunil;Rask, Kimberly
通讯作者：
Rask, Kimberly
影响因子：
24
作者：
Heidenreich, PA;Spertus, JA;Williams, RE
通讯作者：
Williams, RE
DOI：
10.1111/j.1532-5415.2005.53461.x
发表时间：
2005-09-01
影响因子：
6.3
作者：
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通讯作者：
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影响因子：
5.7
作者：
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通讯作者：
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影响因子：
5.9
作者：
Howard, DH;Gazmararian, J;Parker, RM
通讯作者：
Parker, RM