Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells.

Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells.
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DOI:
10.1182/blood-2013-04-494914
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发表时间:
2013-06
期刊:
影响因子:
20.3
通讯作者:
D. Ran;K. Lam;Wei-Jong Shia;Miao-Chia Lo;Jun-Bao Fan;D. Knorr;Patrick I. Ferrell;Zhaohui Ye;Ming Yan;Linzhao Cheng;D. Kaufman;Dong-er Zhang
D. Ran;K. Lam;Wei-Jong Shia;Miao-Chia Lo;Jun-Bao Fan;D. Knorr;Patrick I. Ferrell;Zhaohui Ye;Ming Yan;Linzhao Cheng;D. Kaufman;Dong-er Zhang
中科院分区:
医学1区
文献类型:
--
作者:
D. Ran;K. Lam;Wei-Jong Shia;Miao-Chia Lo;Jun-Bao Fan;D. Knorr;Patrick I. Ferrell;Zhaohui Ye;Ming Yan;Linzhao Cheng;D. Kaufman;Dong-er Zhang

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编者按:在最近一期的《血液》中,Ran等人[1][1]报道了RUNX1a亚型的异位表达有助于从人类胚胎干细胞(HESCs)中产生确定的造血干/祖细胞(HSPC),以及RUNX1a-hESC令人印象深刻的扩增潜力
To the editor: In a recent issue of Blood , Ran et al[1][1] reported that ectopic expression of RUNX1a isoform facilitates the emergence of definitive hematopoietic stem/progenitor cells (HSPCs) from human embryonic stem cells (hESCs), as well as an impressive expansion potential of the RUNX1a-hESC