THE CLINICIAN-ADMINISTERED RATING-SCALE FOR MANIA (CARS-M) - DEVELOPMENT, RELIABILITY, AND VALIDITY

THE CLINICIAN-ADMINISTERED RATING-SCALE FOR MANIA (CARS-M) - DEVELOPMENT, RELIABILITY, AND VALIDITY
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DOI:
10.1016/0006-3223(94)91193-2
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发表时间:
1994-07-15
影响因子:
10.6
通讯作者:
DAVIS, JM
DAVIS, JM
中科院分区:
医学1区
文献类型:
--
作者:
ALTMAN, EG;HEDEKER, DR;DAVIS, JM

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目前有七个罕见的规模可用于评估躁狂症的精神病学。然而,所有这些都有一些限制,可能会限制其临床和研究用途。为了解决这些缺陷,临床医生-管理人员躁狂症评定量表(CARS-M)的开发和规范的96例患者在基线和治疗后的混合诊断。评价者间的可靠性建立在多个评价者观看14个录像访谈和比较个别项目和总分之间的协议。在基线期间对36例患者进行了两次重测信度评估。14名患者中每名患者的5名评分者的项目平均组内相关系数为0.81,总分为0.93。项目的主成分分析显示两个因素:躁狂症,精神病。重测信度是显着的两个因素(范围= 0.78至0.95)。内部效度,比较每个项目与其各自的总因子得分,发现所有项目的显着相关性。CARS-M总分与躁狂评定量表(MRS)总分的相关性为0.94。结果表明,CARS-M是躁狂症神经病学严重程度的可靠和有效的衡量标准,它结合了许多方法上的改进,从而提高了精确度和临床实用性。
There are currently seven raring scales available to assess manic symptomatology. All, however, have some limitations that could restrict their clinical and research utility. To resolve these deficiencies the Clinician-Administered Rating Scale for Mania (CARS-M) was developed and normed on 96 patients with mixed diagnoses during baseline and following treatment. Interrater reliability was established across multiple raters viewing 14 videotaped interviews and comparing agreement among individual items and total scores. Test-retest reliability was assessed on 36 patients twice during baseline. The mean intraclass correlation coefficient among five raters across items for each of the 14 patients was 0.81, and for total scores 0.93. Principal components analysis of items revealed two factors: mania, and psychosis. Test-retest reliability was significant for both factors (range = 0.78 to 0.95). Internal validity, comparing each item with its respective total factor score, revealed significant correlations for all items. Correlation of CARS-M total scores with mania rating scale (MRS) total scores was 0.94. Results indicate the CARS-M is both a reliable and valid measure of the severity of manic symptomotology, which incorporates a number of methodological improvements leading to greater precision and clinical utility.