GRANULOCYTIC SARCOMA SHOWING CHROMOSOMAL CHANGES OTHER THAN THE T(821)
GRANULOCYTIC SARCOMA SHOWING CHROMOSOMAL CHANGES OTHER THAN THE T(821)
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DOI：
10.1016/0165-4608(94)90030-2
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发表时间：
1994-05-01
影响因子：
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通讯作者：
SARIBAN, E
中科院分区：
文献类型：
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作者：
HEIMANN, P;VAMOS, E;SARIBAN, E
粒细胞肉瘤的细胞遗传学分析显示 46,XX,der(X)t(X;1)(q28;q22), inv(3)(p21q27),inv(9)(p13q22),t(12;22)(p11;q11) 核型。此外，骨髓抽吸显示存在具有 46,XX,inv(3)(p21q27),inv(9)(p13q22),t(12;22)(p11;q11) 染色体模式的细胞，而患者患有临床白血病。该病例表明，除经典 t(8;21) 之外的染色体异常也可能与粒细胞肉瘤相关。
Cytogenetic analysis of a granulocytic sarcoma showed a 46,XX,der(X)t(X;1)(q28;q22), inv(3)(p21q27),inv(9)(p13q22),t(12;22)(p11;q11) karyotype. In addition, bone marrow aspirate disclosed the presence of cells with a 46,XX,inv(3)(p21q27),inv(9)(p13q22),t(12;22)(p11;q11) chromosomal pattern while the patient was clinically aleukemic. This case demonstrates that chromosomal abnormalities other than the classical t(8;21) can also be associated with granulocytic sarcoma.