Postprandial Glucose Variability Following Typical Meals in Youth Living with Type 1 Diabetes.
Postprandial Glucose Variability Following Typical Meals in Youth Living with Type 1 Diabetes.
复制标题
DOI：
10.3390/nu16010162
复制
发表时间：
2024-01-04
期刊：
影响因子：
5.9
通讯作者：
Martin CK
中科院分区：
文献类型：
--
作者：
Patton SR;Bergford S;Sherr JL;Gal RL;Calhoun P;Clements MA;Riddell MC;Martin CK
We explored the association between macronutrient intake and postprandial glucose variability in a large sample of youth living with T1D and consuming free-living meals. In the Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) Study, youth took photographs before and after their meals on 3 days during a 10 day observation period. We used the remote food photograph method to obtain the macronutrient content of youth’s meals. We also collected physical activity, continuous glucose monitoring, and insulin use data. We measured glycemic variability using standard deviation (SD) and coefficient of variation (CV) of glucose for up to 3 h after meals. Our sample included 208 youth with T1D (mean age: 14 ± 2 years, mean HbA1c: 54 ± 14.2 mmol/mol [7.1 ± 1.3%]; 40% female). We observed greater postprandial glycemic variability (SD and CV) following meals with more carbohydrates. In contrast, we observed less postprandial variability following meals with more fat (SD and CV) and protein (SD only) after adjusting for carbohydrates. Insulin modality, exercise after meals, and exercise intensity did not influence associations between macronutrients and postprandial glycemic variability. To reduce postprandial glycemic variability in youth with T1D, clinicians should encourage diversified macronutrient meal content, with a goal to approximate dietary guidelines for suggested carbohydrate intake.
影响因子：
5.5
作者：
Spruijt-Metz D;Wen CKF;Bell BM;Intille S;Huang JS;Baranowski T
通讯作者：
Baranowski T
影响因子：
1.1
作者：
Rose MH;Streisand R;Aronow L;Tully C;Martin CK;Mackey E
通讯作者：
Mackey E