Asthma in Pregnancy

Asthma in Pregnancy
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DOI:
10.1056/nejmcp0809942
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发表时间:
2009-04-30
影响因子:
158.5
通讯作者:
Dombrowski, Mitchell P.
Dombrowski, Mitchell P.
中科院分区:
医学1区
文献类型:
--
作者:
Schatz, Michael;Dombrowski, Mitchell P.

文献摘要

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一名23岁的不吸烟妇女(妊娠1,第0段)在怀孕11周时表现出8年的哮喘史,在过去的一年中病情恶化。她报告哮喘症状需要沙丁胺醇每天两到三次,每周两到三个晚上干扰睡眠。怀孕前给她开了皮质类固醇吸入器,但她一直不敢使用。打扫房子会引发哮喘,而她家养猫已经一年了。她的1秒用力呼气量(FEV1)是预测值的75%;服用沙丁胺醇后增加到预测值的88%。她的案件应该如何处理?
A 23-year-old nonsmoking woman (gravida 1, para 0) presents at 11 weeks' gestation with an 8-year history of asthma, which has worsened over the past year. She reports asthma symptoms requiring albuterol two or three times per day and interfering with sleep two or three nights per week. A corticosteroid inhaler was prescribed before pregnancy, but she has been afraid to use it. Cleaning her house triggers asthma, and she has had a cat at home for 1 year. Her forced expiratory volume in 1 second (FEV1) is 75% of the predicted value; it increases to 88% of the predicted value after administration of albuterol. How should her case be managed?