Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS).
Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS).
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DOI：
10.1016/s0140-6736(03)13168-6
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发表时间：
2003-05-03
期刊：
影响因子：
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通讯作者：
Advisors of Expert SARS group of Hospital Authority
中科院分区：
文献类型：
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作者：
Seto WH;Tsang D;Yung RW;Ching TY;Ng TK;Ho M;Ho LM;Peiris JS;Advisors of Expert SARS group of Hospital Authority
我们在香港五家医院进行了一项病例对照研究，其中有 241 名未感染者和 13 名感染者，记录显示在患者护理期间曾接触过 11 名严重急性呼吸系统综合症 (SARS) 指标患者。根据护理 SARS 指标患者时飞沫和接触预防措施中的建议，所有参与者都接受了关于使用口罩、手套、长袍和洗手的调查。报告使用全部四项措施的 69 名员工并未受到感染，而所有受感染的员工都至少省略了一项措施 (p=0·0224)。与不戴口罩 (p=0·0001)、穿防护服 (p=0·006) 和洗手 (p=0·047) 的员工相比，戴口罩 (p=0·0001)、穿防护服 (p=0·006) 和洗手 (p=0·047) 的员工较少被感染，但逐步逻辑回归仅对口罩显着 (p=0·011)。采取飞沫预防和接触预防措施足以显着降低接触 SARS 患者后的感染风险。口罩的防护作用表明，在医院里，感染是通过飞沫传播的。
We did a case-control study in five Hong Kong hospitals, with 241 non-infected and 13 infected staff with documented exposures to 11 index patients with severe acute respiratory syndrome (SARS) during patient care. All participants were surveyed about use of mask, gloves, gowns, and hand-washing, as recommended under droplets and contact precautions when caring for index patients with SARS. 69 staff who reported use of all four measures were not infected, whereas all infected staff had omitted at least one measure (p=0·0224). Fewer staff who wore masks (p=0·0001), gowns (p=0·006), and washed their hands (p=0·047) became infected compared with those who didn't, but stepwise logistic regression was significant only for masks (p=0·011). Practice of droplets precaution and contact precaution is adequate in significantly reducing the risk of infection after exposures to patients with SARS. The protective role of the mask suggests that in hospitals, infection is transmitted by droplets.
DOI：
10.1016/s0140-6736(03)13077-2
发表时间：
2003-04-19
期刊：
Lancet (London, England)
影响因子：
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作者：
Peiris JS;Lai ST;Poon LL;Guan Y;Yam LY;Lim W;Nicholls J;Yee WK;Yan WW;Cheung MT;Cheng VC;Chan KH;Tsang DN;Yung RW;Ng TK;Yuen KY;SARS study group
通讯作者：
SARS study group