The efferent connections of the nucleus accumbens in the lizard Gekko gecko
The efferent connections of the nucleus accumbens in the lizard Gekko gecko
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DOI：
10.1007/bf00215299
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
W. Smeets;L. Medina
中科院分区：
文献类型：
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作者：
W. Smeets;L. Medina
目前对壁虎蜥蜴基底神经节连接的研究表明，伏隔核的传出投射比以前认为的要复杂得多。投射不仅到达白球腹侧、视前区、下丘脑外侧区和腹侧被盖区，而且到达终纹床核、丘脑背内侧核、黑质和脑后多巴胺能细胞群。在伏隔核内观察到额外的投射，并在尾侧观察到臂周区域和中缝上核。此外，本研究的结果表明，对腹侧苍白球和中脑多巴胺能细胞群的伏隔投射具有内侧到外侧的地形组织。这种对壁虎伏隔核传出投射的扩展观点表明，爬行动物和哺乳动物的伏隔核输出系统非常相似。然而，在爬行动物的“边缘回路”中观察到一个显著的差异，与哺乳动物相比，爬行动物的边缘回路似乎没有皮层参与。
The present investigation of connections in the basal ganglia of the lizardGekko geckohas revealed that the efferent projections of the nucleus accumbens are far more elaborate than previously thought. The projections reach not only the ventral pallidum, the preoptic area, the lateral hypothalamic area and the ventral tegmental area, but also the bed nucleus of the stria terminalis, the dorsomedial thalamic nucleus, the substantia nigra and the retrorubral dopaminergic cell group. Additional projections were observed within the nucleus accumbens and, caudally, to the peribrachial region and the superior raphe nucleus. Moreover, the results of the present study indicate that the accumbal projections to both the ventral pallidum and midbrain dopaminergic cell groups have a medial-to-lateral topographical organization. This expanded view of the efferent projections of the nucleus accumbens ofGekko geckosuggests a great resemblance in accumbal output systems between reptiles and mammals. A notable difference, however, is observed in the “limbic loop”, which in reptiles, in contrast to mammals, seems to lack a cortical involvement.