Cancer incidence in the united farmworkers of America (UFW), 1987-1997
Cancer incidence in the united farmworkers of America (UFW), 1987-1997
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DOI：
10.1002/ajim.1125
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发表时间：
2001-11-01
影响因子：
3.5
通讯作者：
Kwong, S
中科院分区：
文献类型：
--
作者：
Mills, PK;Kwong, S
本研究的目的是评估美国农业工人联合会（UFW）成员中的癌症发病率，并检查该组中癌症的特定部位分布以及组织学和诊断时的癌症分期。方法在UFW成员名册和加州癌症登记处数据库之间进行电子记录链接。基于人口的癌症登记，在加州，1987 - 1997年。根据连锁的结果，使用加州西班牙裔人群中癌症的分布作为参考来计算发病率比值比，以确定UFW中特定癌症的风险是高还是低。自第一次加入联盟的调整进行了评估，是在诊断的组织学亚型和阶段的比例分布，再次比较经验的UFW成员的加州西班牙裔population.Results几种类型的癌症升高UFW成员生病比较加州西班牙裔人口。白血病的发病优势比和95%置信限升高（O.R. = 1.59：95%置信区间= 1.07 - 2.37）、胃癌（O.R. = 1.69：95%置信区间= 1.24-2.27）、宫颈癌（O.R. = 1.63：95%置信区间= 1.11 - 2.44）和子宫体癌（O.R. 1.68：95% CI 1.05 - 2.67）。脑癌的发病率也有所上升，但并不显著（O.R. - 1.57：95% CI结论加州农场工人白血病、胃癌、宫颈癌和子宫癌的发病风险较高。白血病和脑癌在UFW成员的组织学分布并没有从一般加州人口的分布不同，虽然在UFW的癌症数量少，阻碍了这些结果的解释。与加州西班牙裔相比，UFW成员在大多数主要癌症部位诊断时经历了晚期疾病，但乳腺癌除外（C）2001 Wiley-Liss，Inc.
Background The purpose of this study was to evaluate cancer incidence in the membership a largely Hispanic farmworker labor union in California, the United Farmworkers of America (UFW) and to examine cancer-site specific distributions as well as histology and stage of cancer at diagnosis in this group.Methods Ali electronic record linkage was conducted between a membership roster of the UFW and the database of the California Cancer Registry, the population-based cancer registry, in California for the years 1987-1997. Based upon the results of the linkage, morbidity odds ratios were calculated using the distribution of cancer in the California Hispanic population as the reference to determine if risk of specific cancers was higher or lower in the UFW. Tune since first joining the union was evaluated, as was the proportional distribution of histologic subtypes and stage at diagnosis, again comparing the experience of the UFW membership to the California Hispanic population.Results Several types of cancer were elevated in the UFW membership ill comparison to the California Hispanic population. Morbidity odds ratios and 95% confidence limits were elevated for leukenzia (O.R. = 1.59: 95% C.I. = 1.07-2.37), stomach cancer (O.R. = 1.69: 95% C.I. = 1.24-2.27), uterine cervix cancer (O.R. = 1.63: 95% C.I. = 1.11-2.44) and uterine corpus cancer (O.R. 1.68: 95% C.I. 1.05-2.67). Brain cancer was also elevated although not significantly so (O.R. - 1.57: 95% C.I. = 0.96-2.53).Conclusions Risk of leukemia, stomach, cervix and uterine cancers was elevated in California farmworkers. The histologic distribution of leukemia and brain cancers within the UFW membership did not differ from the distribution in the general California population although small numbers of cancers in the UFW hindered interpretation of these results. Members of the UFW experienced later stage of disease at diagnosis ill comparison to California Hispanics for most major cancer sites but not for breast cancer (C) 2001 Wiley-Liss, Inc.