A catalyst-controlled switchable reaction of -keto acids to silyl glyoxylates
A catalyst-controlled switchable reaction of -keto acids to silyl glyoxylates
复制标题
催化剂控制的α-酮酸生成乙醛酸硅酯的可切换反应
DOI：
10.1039/c8ob00740c
复制
发表时间：
2018
影响因子：
3.2
通讯作者：
Lei Wang
中科院分区：
文献类型：
--
作者：
Man-Yi Han;Hong Pan;Jing Lin;Wei Li;Pinhua Li;Lei Wang
在温和条件下，β-酮酸与乙醛酸甲硅烷基酯反应，得到两种不同的产物，收率较高。与脱羧加成-Brook重排反应相比，使用简单的双功能有机催化剂硫脲衍生物代替DABCO，可以控制脱羧加成产物。这一新的乙醛酸硅酯反应模型为合成有机硅化合物提供了一条简便的途径。
A catalyst-controlled switchable reaction of β-keto acids to silyl glyoxylates was developed under mild conditions, providing two distinct products in good yields. Compared to decarboxylative addition-Brook rearrangement, the decarboxylative addition products could be controlled by using a simple bifunctional organocatalyst thiourea derivative instead of DABCO. This new reaction model of silyl glyoxylates offered a facile and alternative route to organosilicon compounds.