Musculoskeletal ultrasonography assists the diagnostic performance of the 2010 classification criteria for rheumatoid arthritis
Musculoskeletal ultrasonography assists the diagnostic performance of the 2010 classification criteria for rheumatoid arthritis
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DOI：
10.3109/s10165-012-0628-7
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发表时间：
2013-01
影响因子：
2.2
通讯作者：
S. Kawashiri;Takahisa Suzuki;A. Okada;S. Yamasaki;M. Tamai;Hideki Nakamura;T. Origuchi;A. Mizokami;M. Uetani;K. Aoyagi;K. Eguchi;A. Kawakami
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文献类型：
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作者：
S. Kawashiri;Takahisa Suzuki;A. Okada;S. Yamasaki;M. Tamai;Hideki Nakamura;T. Origuchi;A. Mizokami;M. Uetani;K. Aoyagi;K. Eguchi;A. Kawakami
我们调查了肌肉骨骼超声检查（MSKUS）是否有助于2010年类风湿性关节炎（RA）分类criteria.MethodsSixty-nine早期关节炎患者的诊断性能。没有一个病人接受过治疗。在22个部位的双侧腕关节和手指关节的MSKUS中，通过灰阶和能量多普勒（PD）评估获得的结果在半定量量表上从0到3进行分级。还检查了手腕和手指关节的普通磁共振成像（MRI）。RA的诊断定义为在前3个月内开始使用缓解疾病的抗风湿药物。患者的诊断性能进行了评估，在入口处使用2010年RA分类标准与MSKUS.ResultsThe不可或缺的MSKUS发现区分RA是一个PD 2级或3级，上级2010年RA分类标准或MRI证实的骨水肿的存在。我们认为，PD 2级或3级的2010年RA分类标准的决策树算法具有最佳的区分能力。结论MSKUS，特别是在PD信号较强的情况下，对于辅助2010年RA分类标准在RA早期识别中的诊断性能非常有用。
ObjectiveWe investigated whether musculoskeletal ultrasonography (MSKUS) assists the diagnostic performance of the 2010 rheumatoid arthritis (RA) classification criteria.MethodsSixty-nine early arthritis patients were consecutively enrolled. None of the patients had been treated. In MSKUS of bilateral wrist and finger joints from 22 sites, the findings obtained by gray-scale and power Doppler (PD) assessment were graded on a semiquantitative scale from 0 to 3. Plain magnetic resonance imaging (MRI) of both wrist and finger joints was also examined. Diagnosis of RA was defined by the initiation of disease-modifying antirheumatic drugs within the first 3 months. The diagnostic performance of the patients was evaluated at entry using 2010 RA classification criteria in conjunction with MSKUS.ResultsThe indispensable MSKUS finding for differentiating RA was the presence of a PD grade 2 or 3 that was superior to 2010 RA classification criteria or MRI-proven bone edema. We propose that the decision tree algorithm of 2010 RA classification criteria with PD grade 2 or 3 reveals the best discriminative ability.ConclusionMSKUS, especially with a strong PD signal, is very useful to assist the diagnostic performance of the 2010 RA classification criteria in the early recognition of RA.