Premarket evaluation of a commercial glycoprotein G-based enzyme immunoassay for herpes simplex virus type-specific antibodies
Premarket evaluation of a commercial glycoprotein G-based enzyme immunoassay for herpes simplex virus type-specific antibodies
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DOI：
10.1128/jcm.36.1.294-295.1998
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发表时间：
1998-01-01
影响因子：
9.4
通讯作者：
Schnorenberg, L
中科院分区：
文献类型：
--
作者：
Ashley, RL;Wu, LX;Schnorenberg, L
以糖蛋白G为基础的酶免疫分析法(GG-EIA)和免疫印迹法(WE)检测193份血清标本中的单纯疱疹病毒1型(HSV-1)和单纯疱疹病毒2型(HSV-2)特异性抗体。HSV-1的敏感性为95%，特异性为96%。HSV-2的敏感性为98%，特异性为97%。在13份GG-EIA结果可疑的血清样本中，有12份用WB进行了血清分型。
A new commercial glycoprotein G-based enzyme immunoassay (gG-EIA) was compared with Western blotting (WE) for detection of herpes simplex virus type 1 (HSV-1) or HSV-2 type specific antibodies in 193 serum samples. Sensitivity for HSV-1 was 95%; specificity was 96%. Sensitivity for HSV-2 was 98%; specificity was 97%. Twelve of 13 serum samples with equivocal gG-EIA results were serotyped by WB.