Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents:: An echocardiographic study
Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents:: An echocardiographic study
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DOI：
10.1016/j.echo.2008.02.006
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发表时间：
2008-08-01
影响因子：
6.5
通讯作者：
Humes, Richard A.
中科院分区：
文献类型：
--
作者：
Pettersen, Michael D.;Du, Wei;Humes, Richard A.
背景资料：先天性和后天性心脏病患儿的护理决策仍然依赖于使用二维超声心动图对心脏结构的详细测量。计算的z分数通常用于将这些测量结果标准化为患者的身体尺寸。文献中现有的正常数据受到样本量小、测量的心脏结构数量少以及用于计算z评分的数据不足的限制。因此，我们试图开发一个大型的儿科队列中使用现代超声心动图设备，z分数可以calculated.Methods：二维和M型超声心动图进行规范的数据在782例患者的年龄范围从1天到18岁。测量了21个单独的心脏结构。回归方程推导出的各种心脏结构的大小与体表面积。数据以图形方式呈现，回归方程推导出心脏尺寸与体表面积的关系。结论：所提出的数据将允许计算超声心动图测量的心脏结构的z分数。这些信息将对临床医生照顾已知或疑似心脏病的婴儿和儿童有价值。
Background: Decision making in the care of pediatric patients with congenital and acquired heart disease remains reliant on detailed measurements of cardiac structures using 2-dimensional echocardiography. Calculated z scores are often used to normalize these measurements to the patient's body size. Existing normal data in the literature are limited by small sample size, small numbers of measured cardiac structures, and inadequate data for the calculation of z scores. Accordingly, we sought to develop normative data in a large pediatric cohort using modern echocardiographic equipment from which z scores could be calculated.Methods: Two-dimensional and M-mode echocardiography was performed in 782 patients ranging in age from 1 day to 18 years. Measurements were made of 21 individual cardiac structures. Regression equations were derived to relate the size of the various cardiac structures to body surface area. Data are presented graphically, and regression equations are derived relating cardiac dimension to body surface area.Conclusion: The presented data will allow the calculation of z scores for echocardiographically measured cardiac structures. This information will be valuable for clinicians caring for infants and children with known or suspected cardiac disease.