First record of L-quebrachitol in Allophylus edulis (Sapindaceae)
First record of L-quebrachitol in Allophylus edulis (Sapindaceae)
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DOI：
10.1016/j.carres.2008.07.014
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发表时间：
2008-10-13
影响因子：
3.1
通讯作者：
Rossini, Carmen
中科院分区：
文献类型：
--
作者：
Diaz, Martina;Gonzalez, Andres;Rossini, Carmen
异叶豆（Allophylus edulis），俗称“Chal chal”，是无患子科的一个成员，分布于乌拉圭和巴西本土植物群。在对来自两个分化良好的地理区域（巴西圣保罗的阿西斯和乌拉圭卡内洛内斯的圣露西亚）的两个Chal chal标本进行植物化学分析期间，从两个样品中分离出大量的L-白坚木醇。从两种植物样品浸渍获得的乙醇树枝提取物进行分离。将白色易于区分的晶体机械分离、洗涤，并通过1D和2D NMR实验和MS数据表征。这种技术证实，从这两个国家收集的来源中分离出的晶体产生了相同的化合物，L-白坚木醇，这是一种以前没有报道过的这种物种的天然产物，也是一种被研究作为糖尿病患者糖替代品的天然产物。值得注意的是，A. edulis可能是解释其民族植物学用途的化学基础，因为在当地传统医学实践中，这种植物的输液被用来治疗糖尿病。(c)2008爱思唯尔有限公司保留所有权利。
Allophylus edulis, commonly called 'Chal chal', is a member of the Sapindaceae occurring in the Uruguayan and Brazilian native flora. During the phytochemical analysis of two Chal chal specimens from two welldifferentiated geographical zones (Assis, Sao Paulo, Brazil, and Santa Lucia, Canelones, Uruguay), considerable amounts Of L-quebrachitol were isolated from both samples. The isolation was carried out from the ethanolic twig extracts obtained by maceration of both vegetal samples. White easily distinguishable crystals were mechanically separated, washed, and characterized by 1D and 2D NMR experiments and by MS data. Such techniques confirmed that the crystals isolated from sources collected in both countries resulted in the same compound, L-quebrachitol, a natural product not previously reported for this species and one that has been investigated as a sugar substitute for diabetics. Worthy of note, the content of L-quebrachitol in A. edulis may be the chemical basis to explain its ethnobotanical uses, since infusions of this plant are used to treat diabetes in the practice of local traditional medicine. (c) 2008 Elsevier Ltd. All rights reserved.